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DNA torsion dynamics is essential in the transcription process; a simple model for it, in reasonable agreement with experimental observations, has been proposed by Yakushevich (Y) and developed by several authors; in this, the DNA subunits…

Biomolecules · Quantitative Biology 2009-11-13 M. Cadoni , R. De Leo , G. Gaeta

The Yakushevich (Y) model provides a very simple pictures of DNA torsion dynamics, yet yields remarkably correct predictions on certain physical characteristics of the dynamics. In the standard Y model, the interaction between bases of a…

Biomolecules · Quantitative Biology 2015-06-26 G. Gaeta

The Yakushevich model of DNA torsion dynamics supports soliton solutions, which are supposed to be of special interest for DNA transcription. In the discussion of the model, one usually adopts the approximation $\ell_0 \to 0$, where…

Biomolecules · Quantitative Biology 2009-11-13 G. Gaeta

In the present paper we investigate the influence of inhomogeneities in the dynamics and stability of DNA open states, modeled as propagating solitons in the spirit of a Generalized Yakushevish Model. It is a direct consecuence of our model…

Pattern Formation and Solitons · Physics 2009-11-07 Luis Morales Molina , Owen Fernandez Piedra

DNA torsion dynamics is essential in the transcription process; simple models for it have been proposed by several authors, in particular Yakushevich (Y model). These are strongly related to models of DNA separation dynamics such as the one…

Biomolecules · Quantitative Biology 2009-11-13 Mariano Cadoni , Roberto De Leo , Sergio Demelio , Giuseppe Gaeta

The approach for the description of the DNA conformational transformations on the mesoscopic scales in the frame of the double helix is presented. Due to consideration of the joint motions of DNA structural elements along the conformational…

Biomolecules · Quantitative Biology 2009-09-29 S. N. Volkov

We here examine the nonlinear dynamics of artificial homogeneous DNA chain relying on the plain-base rotator model. It is shown that such dynamics can exhibit kink and antikink solitons of sine-Gordon type. In that respect we propose…

Biological Physics · Physics 2015-06-05 S. Zdravković , M. V. Satarić , M. Daniel

It has been suggested by several authors that nonlinear excitations, in particular solitary waves, could play a fundamental functional role in the process of DNA transcription, effecting the opening of the double chain needed for RNA…

Other Quantitative Biology · Quantitative Biology 2016-09-08 G. Gaeta

In this work we analyze the possibility that soliton dynamics in a simple nonlinear model allows functionally relevant predictions of the behaviour of DNA. This suggestion was first put forward by Salerno [Phys. Rev. A, vol. 44, p. 5292…

Genomics · Quantitative Biology 2009-11-13 Sara Cuenda , Angel Sanchez , Niurka R. Quintero

We investigate the nonlinear dynamics of the Peyrard-Bishop DNA model taking into account site dependent inhomogeneities. By means of the multiple-scale expansion in the semi-discrete approximation, the dynamics is governed by the perturbed…

Biological Physics · Physics 2018-07-20 Joseph Brizar Okaly , Alain Mvogo , Rosalie Laure Woulache , Timoleon Crepin Kofane

We study the tautomeric transitions in base pairs of DNA considering elastic properties of DNA as classical and tunneling of protons as quantum, and show that the dynamics of the transitions admits of soliton like solutions whose shape and…

Soft Condensed Matter · Physics 2007-05-23 V. L. Golo , Yu. S. Volkov

Dynamics of topological solitons describing open states in the DNA double helix are studied in the frameworks of the model which takes into account asymmetry of the helix. It is shown that three types of topological solitons can occur in…

Biological Physics · Physics 2009-11-07 L. V. Yakushevich , A. V. Savin , L. I. Manevitch

The modelling of DNA mechanics under external constraints is discussed. Two analytical models are widely known, but disagree for instance on the value of the torsional modulus. The origin of this embarassing situation is located in the…

Soft Condensed Matter · Physics 2009-09-07 Vincent Rossetto

It was first suggested by Englander et al to model the nonlinear dynamics of DNA relevant to the transcription process in terms of a chain of coupled pendulums. In a related paper [q-bio.BM/0604014] we argued for the advantages of an…

Biomolecules · Quantitative Biology 2015-06-26 M. Cadoni , R. De Leo , G. Gaeta

We construct a theoretical model for the dynamics of a microscale colloidal particle, modeled as an interval, moving horizontally on a DNA-coated surface, modelled as a line coated with springs that can stick to the interval. Averaging over…

Soft Condensed Matter · Physics 2018-09-28 James P. Lee-Thorp , Miranda Holmes-Cerfon

We study nonlinear dynamics of a periodic inhomogeneous DNA double helical chain under dynamic plane-base rotator model by considering angular rotation of bases in a plane normal to the helical axis. The dynamics is governed by a perturbed…

Pattern Formation and Solitons · Physics 2008-07-16 M. Daniel , V. Vasumathi

We present a self-contained theory for the mechanical response of DNA in single molecule experiments. Our model is based on a 1D continuum description of the DNA molecule and accounts both for its elasticity and for DNA-DNA electrostatic…

Biomolecules · Quantitative Biology 2015-05-13 N. Clauvelin , B. Audoly , S. Neukirch

We study the nonlinear dynamics of a deformed Deoxyribonucleic acid (DNA) molecular chain which is governed by a perturbed sine-Gordon equation coupled with a linear wave equation representing the lattice deformation. The DNA chain…

Pattern Formation and Solitons · Physics 2009-11-13 V. Vasumathi , M. Daniel

The twisting deformation of mechanically stretched DNA molecules is studied by a coarse grained Hamiltonian model incorporating the fundamental interactions that stabilize the double helix and accounting for the radial and angular base pair…

Soft Condensed Matter · Physics 2017-12-15 Marco Zoli

Many physical systems can be mapped onto solved or "solvable" models of magnetism. In this work, we have mapped the statistical mechanics of columnar phases of ideally helical rigid DNA -- subject to the earlier found unusual, frustrated…

Biological Physics · Physics 2009-11-10 A. Wynveen , D. J. Lee , A. A. Kornyshev
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