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We show that textual analysis of microbial genomes reveal telling footprints of the early evolution of the genomes. The frequencies of word occurrence of random DNA sequences considered as texts in their four nucleotides are expected to…

Biological Physics · Physics 2007-05-23 Li-Ching Hsieh , Liaofu Luo , HC Lee

Recent advances in high-throughput genomics technologies have resulted in the sequencing of large numbers of (near) complete genomes. These genome sequences are being mined for important functional elements, such as genes. They are also…

Genomics · Quantitative Biology 2007-05-23 Lior Pachter

We present a simple and effective approach to incorporating syntactic structure into neural attention-based encoder-decoder models for machine translation. We rely on graph-convolutional networks (GCNs), a recent class of neural networks…

Computation and Language · Computer Science 2020-06-22 Jasmijn Bastings , Ivan Titov , Wilker Aziz , Diego Marcheggiani , Khalil Sima'an

We investigate the possibility of encoding multiple solutions of a problem in a single chromosome. The best solution encoded in an individual will represent (will provide the fitness of) that individual. In order to obtain some benefits the…

Neural and Evolutionary Computing · Computer Science 2021-10-22 Mihai Oltean

A central challenge in the origin of life is understanding how catalytic peptide-like polymers and information-bearing nucleic acid-like polymers emerged as an interde-pendent system. This study constructs a primordial cognitive model…

Other Quantitative Biology · Quantitative Biology 2026-05-11 Takeshi Ishida

Present day data allow significant reconsideration of ideas on mechanisms underlying the degeneracy in the genetic code. Here a hypothesis is presented which links the degeneracy to possible conformational alterations in the codon-anticodon…

Biological Physics · Physics 2013-10-14 Denis A. Semyonov

We present new techniques for synthesizing programs through sequences of mutations. Among these are (1) a method of local scoring assigning a score to each expression in a program, allowing us to more precisely identify buggy code, (2)…

Neural and Evolutionary Computing · Computer Science 2023-01-26 Max Vistrup

This paper proposes Genetic Algorithm with Border Trades (GAB), a novel modification of the standard genetic algorithm that enhances exploration by incorporating new chromosome patterns in the breeding process. This approach significantly…

Machine Learning · Computer Science 2025-06-27 Qingchuan Lyu

Molecular biology is a nanotechnology that works--it has worked for billions of years and in an amazing variety of circumstances. At its core is a system for acquiring, processing and communicating information that is universal, from…

Genomics · Quantitative Biology 2016-12-21 Apoorva D. Patel

Artificial intelligence generated content (AIGC), a rapidly advancing technology, is transforming content creation across domains, such as text, images, audio, and video. Its growing potential has attracted more and more researchers and…

Artificial Intelligence · Computer Science 2026-03-03 Chengzhang Zhu , Luobin Cui , Ying Tang , Jiacun Wang

Universal coding of integers~(UCI) is a class of variable-length code, such that the ratio of the expected codeword length to $\max\{1,H(P)\}$ is within a constant factor, where $H(P)$ is the Shannon entropy of the decreasing probability…

Information Theory · Computer Science 2022-04-18 Wei Yan , Sian-Jheng Lin , Yunghsiang S. Han

New developments are presented in the framework of the model introduced by the authors in refs. [1,2] and in which nucleotides as well as codons are classified in crystal bases of the quantum group U_q(sl(2)+sl(2)) in the limit q -> 0. An…

Biological Physics · Physics 2007-05-23 L. Frappat , A. Sciarrino , P. Sorba

The number of available genomes of prokaryotic organisms is rapidly growing enabling comparative genomics studies. The comparison of genomes of organisms with a common phenotype, habitat or phylogeny often shows that these genomes share…

Genomics · Quantitative Biology 2023-05-11 Giorgio Gonnella

This paper presents a novel design framework for protograph-based LDPC codes that simultaneously achieves full diversity in block-fading channels (BFCs) and nearcapacity performance in additive white Gaussian noise channels (AWGNCs). By…

Information Theory · Computer Science 2026-02-03 Inki Kim , Hyuntae Ahn , Yongjune Kim , Hee-Youl Kwak , Dae-Young Yun , Sang-Hyo Kim

We introduce the star cluster evolution code Evolve Me A Cluster of StarS (EMACSS), a simple yet physically motivated computational model that describes the evolution of some fundamental properties of star clusters in static tidal fields.…

Astrophysics of Galaxies · Physics 2015-06-04 Poul E. R. Alexander , Mark Gieles

The importance of the notion of symmetry in physics is well established: could it also be the case for the genetic code? In this spirit, a model for the Genetic Code based on continuous symmetries and entitled the "Crystal Basis Model" has…

Other Quantitative Biology · Quantitative Biology 2017-04-05 A. Sciarrino , P. Sorba

Of the twenty amino acids used in proteins, ten were formed in Miller's atmospheric discharge experiments. The two other major proposed sources of prebiotic amino acid synthesis include formation in hydrothermal vents and delivery to Earth…

Earth and Planetary Astrophysics · Physics 2015-05-13 Paul G. Higgs , Ralph E. Pudritz

Cartesian Genetic Programming (CGP) suffers from a specific limitation: Positional bias, a phenomenon in which mostly genes at the start of the genome contribute to a program output, while genes at the end rarely do. This can lead to an…

Neural and Evolutionary Computing · Computer Science 2024-10-02 Henning Cui , Andreas Margraf , Jörg Hähner

The standard genetic code is well known to be optimized for minimizing the phenotypic effects of single nucleotide substitutions, a property that was likely selected for during the emergence of a universal code. Given the fitness advantage…

Populations and Evolution · Quantitative Biology 2017-11-28 Shubham Tripathi , Michael W. Deem

We introduce version two of the fast star cluster evolution code Evolve Me A Cluster of StarS (EMACSS). The first version (Alexander & Gieles) assumed that cluster evolution is balanced for the majority of the life-cycle, meaning that the…

Astrophysics of Galaxies · Physics 2015-06-17 Mark Gieles , Poul Alexander , Henny Lamers , Holger Baumgardt
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