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Pinched flow fractionation is shown to be an efficient and selective way to quickly separate particles by size in a very polydisperse semi-concentrated suspension. In an effort to optimize the method, we discuss the quantitative influence…

Fluid Dynamics · Physics 2012-04-17 Aparna Srivastav , Thomas Podgorski , Gwennou Coupier

We present a computational investigation of the mechanism governing size-based particle separation in microfluidic pinched flow fractionation. We study the behavior of particles moving through a pinching gap (i.e., a constriction in the…

Fluid Dynamics · Physics 2016-05-04 Sumedh R. Risbud , German Drazer

Froth flotation predominantly separates particles according to their differences in wettability. However, other particle properties such as size, shape or density significantly influence the separation outcome as well. Froth flotation is…

Materials Science · Physics 2024-01-24 Johanna Sygusch , Thomas Wilhelm , Orkun Furat , Kai Bachmann , Volker Schmidt , Martin Rudolph

Particle Flow Filters perform the measurement update by moving particles to a different location rather than modifying the particles' weight based on the likelihood. Their movement (flow) is dictated by a drift term, which continuously…

Computational Engineering, Finance, and Science · Computer Science 2025-07-04 Simone Servadio

Efficient particle sorting in microfluidic systems is vital for advancements in biomedical diagnostics and industrial applications. This study numerically investigates particle migration and passive sorting in symmetric serpentine…

Fluid Dynamics · Physics 2025-09-16 Sayan Karmakar , Anish Pal , Sourav Sarkar , Achintya Mukhopadhyay

Particles suspended in fluid flow through a closed duct can focus to specific stable locations in the duct cross-section due to hydrodynamic forces arising from the inertia of the disturbed fluid. Such particle focusing is exploited in…

Fluid Dynamics · Physics 2023-01-25 Rahil Valani , Brendan Harding , Yvonne Stokes

In this work, we derive particle schemes, based on micro-macro decomposition, for linear kinetic equations in the diffusion limit. Due to the particle approximation of the micro part, a splitting between the transport and the collision part…

Numerical Analysis · Mathematics 2017-01-19 Anaïs Crestetto , Nicolas Crouseilles , Mohammed Lemou

Motivated by recent experimental advances (Stroock et al. 2002) in microfluidic mixers, we study the passive mixing and flow properties of a patterned microchannel by means of computational fluid dynamics (CFD). Such geometries overcome the…

Soft Condensed Matter · Physics 2007-05-23 J. P. Bennett , C. H. Wiggins

Most technical polymers and many biopolymers contain very different molecular species (unlike chain length, molecular architecture and/or chemical composition) in contrast to pure low molecular weight compounds. This inconsistent…

Materials Science · Physics 2007-06-25 John Eckelt , B. A. Wolf

A new method of particle size analysis of micrometer-sized particles is discussed. The improved method of sedimentation analysis with magnetic fluids has the potential and versatility to characterize polydisperse systems.

Soft Condensed Matter · Physics 2011-04-05 Yury Dikansky , Arthur Zakinyan , Marita Bedganian

We report the pinching of an elongated liquid droplet that is confined in a rectangular microchannel. The droplet pinching is induced by a local variation of the channel topography and can lead to its break-up. The modification of the…

We present a particle separation mechanism which induces motion of particles of different sizes in opposite directions. The mechanism is based on the combined action of a driving force and an entropic rectification of the Brownian…

Statistical Mechanics · Physics 2012-02-10 D. Reguera , A. Luque , P. S. Burada , G. Schmid , J. M. Rubí , P. Hänggi

We propose a method to separate enantiomers in microfluidic or nanofluidic channels. It requires flow profiles which break chiral symmetry and have regions with high local shear. Such profiles can be generated in channels confined by walls…

Fluid Dynamics · Physics 2012-04-19 Sebastian Meinhardt , Jens Smiatek , Ralf Eichhorn , Friederike Schmid

Particle-wall interactions play a crucially important role in various applications such as microfluidic devices for cell sorting, particle separation, entire class of hydrodynamic filtration and its derivatives, etc. Yet, accurate…

Fluid Dynamics · Physics 2025-03-18 Aryan Mehboudi , Shrawan Singhal , S. V. Sreenivasan

Particle size is a key variable in understanding the behaviour of the particulate products that underpin much of our modern lives. Typically obtained from suspensions at rest, measuring the particle size under flowing conditions would…

Soft Condensed Matter · Physics 2021-07-22 James A Richards , Vincent A Martinez , Jochen Arlt

Fitting probabilistic models to data is often difficult, due to the general intractability of the partition function. We propose a new parameter fitting method, Minimum Probability Flow (MPF), which is applicable to any parametric model. We…

Machine Learning · Computer Science 2020-07-21 Jascha Sohl-Dickstein , Peter Battaglino , Michael R. DeWeese

Microparticle laser fragmentation in liquids has emerged as a promising approach to generate nanoparticles with high efficiency. Despite its advantages, the underlying fragmentation mechanisms, their connection to the nanoparticle size…

Fractal channels have significant applications in fields such as microfluidic chips and in vitro diagnostics. However, there is currently insufficient understanding and recognition of fluid flow within fractal channels. In this paper, the…

Fluid Dynamics · Physics 2024-09-20 Jun Hu , Zhan-Long Wang

The recent advent of advanced microfabrication capabilities of microfluidic devices has driven attention towards the behavior of particles in inertial flows within microchannels for applications related to the separation and concentration…

Fluid Dynamics · Physics 2018-12-03 Mike Garcia , Sumita Pennathur

We present a numerical study of the effect that fluid and particle inertia have on the motion of suspended spherical particles through a geometric constriction to understand analogous microfluidic settings, such as pinched flow…

Fluid Dynamics · Physics 2013-06-20 Sumedh R. Risbud , Mingxiang Luo , Joelle Frechette , German Drazer
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