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The Automated Protein Structure Analysis (APSA) method is used for the classification of supersecondary structures. Basis for the classification is the encoding of three-dimensional (3D) residue conformations into a 16-letter code (3D-1D…

Quantitative Methods · Quantitative Biology 2008-11-24 Sushilee Ranganathan , Dmitry Izotov , Elfi Kraka , Dieter Cremer

Cross-lingual plagiarism (CLP) occurs when texts written in one language are translated into a different language and used without acknowledging the original sources. One of the most common methods for detecting CLP requires online machine…

Computation and Language · Computer Science 2018-01-04 Victor Thompson

Aligning multiple protein structures can yield valuable information about structural similarities among related proteins, as well as provide insight into evolutionary relationships between proteins in a family. We have developed an…

Biomolecules · Quantitative Biology 2019-11-07 Paul Shealy , Homayoun Valafar

Protein structure prediction is one of the most important problems in computational biology. The most successful computational approach, also called template-based modeling, identifies templates with solved crystal structures for the query…

Biomolecules · Quantitative Biology 2013-06-20 Jian Peng

The closest pair of points problem or closest pair problem (CPP) is an important problem in computational geometry where we have to find a pair of points from a set of points in metric space with the smallest distance between them. This…

Data Structures and Algorithms · Computer Science 2020-08-03 Subrata Saha , Ahmed Soliman , Sanguthevar Rajasekaran

Superpixels have become very popular in many computer vision applications. Nevertheless, they remain underexploited since the superpixel decomposition may produce irregular and non stable segmentation results due to the dependency to the…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Rémi Giraud , Vinh-Thong Ta , Aurélie Bugeau , Pierrick Coupé , Nicolas Papadakis

Crystal Structure Prediction (CSP) of molecular crystals plays a central role in applications, such as pharmaceuticals and organic electronics. CSP is challenging and computationally expensive due to the need to explore a large search space…

Previous partial permutation synchronization (PPS) algorithms, which are commonly used for multi-object matching, often involve computation-intensive and memory-demanding matrix operations. These operations become intractable for large…

Computer Vision and Pattern Recognition · Computer Science 2022-04-01 Shaohan Li , Yunpeng Shi , Gilad Lerman

Recent advances in geometric deep learning and generative modeling have enabled the design of novel proteins with a wide range of desired properties. However, current state-of-the-art approaches are typically restricted to generating…

Biomolecules · Quantitative Biology 2025-08-26 Vsevolod Viliuga , Leif Seute , Nicolas Wolf , Simon Wagner , Arne Elofsson , Jan Stühmer , Frauke Gräter

In this paper we report on an algorithm for aligning multiple protein structures. The algorithm has been tested on a variety of inputs and it performs well in comparison to well-known algorithms for this problem.

Computational Engineering, Finance, and Science · Computer Science 2014-12-30 Kaushik Roy , Satish Ch. Panigrahi , Asish Mukhopadhyay

Protein retrieval, which targets the deconstruction of the relationship between sequences, structures and functions, empowers the advancing of biology. Basic Local Alignment Search Tool (BLAST), a sequence-similarity-based algorithm, has…

Information Retrieval · Computer Science 2025-01-06 Yuxuan Wu , Xiao Yi , Yang Tan , Huiqun Yu , Guisheng Fan , Gaowei Zheng

A similarity join aims to find all similar pairs between two collections of records. Established approaches usually deal with synthetic differences like typos and abbreviations, but neglect the semantic relations between words. Such…

Information Retrieval · Computer Science 2018-10-30 Pengfei Xu , Jiaheng Lu

Correlation clustering is a widely studied framework for clustering based on pairwise similarity and dissimilarity scores, but its best approximation algorithms rely on impractical linear programming relaxations. We present faster…

Data Structures and Algorithms · Computer Science 2022-06-27 Nate Veldt

Vision-language models (VLMs) such as CLIP are trained via contrastive learning between text and image pairs, resulting in aligned image and text embeddings that are useful for many downstream tasks. A notable drawback of CLIP, however, is…

Machine Learning · Computer Science 2025-07-08 Dylan Sam , Devin Willmott , Joao D. Semedo , J. Zico Kolter

Due to the increased availability of large datasets of biological sequences, the tools for sequence comparison are now relying on efficient alignment-free approaches to a greater extent. Most of the alignment-free approaches require the…

Data Structures and Algorithms · Computer Science 2018-07-23 F. Garofalo , G. Rosone , M. Sciortino , D. Verzotto

Modeling fine-grained speaking styles remains challenging for language-speech representation pre-training, as existing speech-text models are typically trained with coarse captions or task-specific supervision, and scalable fine-grained…

Audio and Speech Processing · Electrical Eng. & Systems 2026-04-21 Yifan Yang , Bing Han , Hui Wang , Wei Wang , Ziyang Ma , Long Zhou , Zengrui Jin , Guanrou Yang , Tianrui Wang , Xu Tan , Xie Chen

Feature selection has been proven a powerful preprocessing step for high-dimensional data analysis. However, most state-of-the-art methods tend to overlook the structural correlation information between pairwise samples, which may…

Machine Learning · Computer Science 2019-07-02 Lu Bai , Lixin Cui , Yue Wang , Philip S. Yu , Edwin R. Hancock

Contrastive Language and Image Pairing (CLIP), a transformative method in multimedia retrieval, typically trains two neural networks concurrently to generate joint embeddings for text and image pairs. However, when applied directly, these…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Konstantin Schall , Kai Uwe Barthel , Nico Hezel , Klaus Jung

The structure of a protein is crucial in determining its functionality, and is much more conserved than sequence during evolution. A key task in structural biology is to compare protein structures in order to determine evolutionary…

Methodology · Statistics 2019-11-06 Christopher Fallaize , Peter Green , Kanti Mardia , Stuart Barber

Referring image segmentation aims at localizing all pixels of the visual objects described by a natural language sentence. Previous works learn to straightforwardly align the sentence embedding and pixel-level embedding for highlighting the…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 Zicheng Zhang , Yi Zhu , Jianzhuang Liu , Xiaodan Liang , Wei Ke