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Existing theories for the evolution of aging and death treat senescence as a side-effect of strong selection for fertility. These theories are well-developed mathematically, but fit poorly with emerging experimental data. The data suggest…

Populations and Evolution · Quantitative Biology 2007-05-23 Josh Mitteldorf

In this paper, we introduce a general numerical method to approximate the reproduction numbers of a large class of multi-group, age-structured, population models with a finite age span. To provide complete flexibility in the definition of…

Populations and Evolution · Quantitative Biology 2024-03-21 Simone De Reggi , Francesca Scarabel , Rossana Vermiglio

Biological evolution is realised through the same mechanisms of birth and death that underlie change in population density. The deep interdependence between ecology and evolution is well-established, and recent models focus on integrating…

Populations and Evolution · Quantitative Biology 2025-10-14 A. Bradley Duthie , Victor J. Luque

Mathematical models of biological populations commonly use discrete structure classes to capture trait variation among individuals (e.g. age, size, phenotype, intracellular state). Upscaling these discrete models into continuum descriptions…

Populations and Evolution · Quantitative Biology 2026-03-18 Eleonora Agostinelli , Keith L. Chambers , Helen M. Byrne , Mohit P. Dalwadi

Coevolving and competing species or game-theoretic strategies exhibit rich and complex dynamics for which a general theoretical framework based on finite populations is still lacking. Recently, an explicit mean-field description in the form…

Statistical Mechanics · Physics 2007-05-23 Arne Traulsen , Jens Christian Claussen , Christoph Hauert

We consider a stochastic individual-based model of adaptive dynamics for an asexually reproducing population with mutation. Biologically motivated by the influence of seasons or the variation of drug concentration during medical treatment,…

Probability · Mathematics 2025-03-26 Manuel Esser , Anna Kraut

We consider the well-posedness of models involving age structure and non-linear diffusion. Such problems arise in the study of population dynamics. It is shown how diffusion and age boundary conditions can be treated that depend…

Analysis of PDEs · Mathematics 2008-10-31 Christoph Walker

We describe the simulation method of modelling the population evolution using Monte Carlo based on the Penna model. Individuals in the populations are represented by their diploid genomes. Genes expressed after the minimum reproduction age…

Genomics · Quantitative Biology 2009-01-13 Agnieszka Laszkiewicz , Przemyslaw Biecek , Katarzyna Bonkowska , Stanislaw Cebrat

We investigate the evolutionary dynamics of a population structured in phenotype, subjected to trait dependent selection with a linearly moving optimum and an asexual mode of reproduction. Our model consists of a non-local and non-linear…

Analysis of PDEs · Mathematics 2021-12-09 Raphaël Forien , Jimmy Garnier , Florian Patout

We analyze the long-term stability of a stochastic model designed to illustrate the adaptation of a population to variation in its environment. A piecewise-deterministic process modeling adaptation is coupled to a Feller logistic diffusion…

Probability · Mathematics 2021-09-14 Aurélien Velleret

Community assembly is studied using individual-based multispecies models. The models have stochastic population dynamics with mutation, migration, and extinction of species. Mutants appear as a result of mutation of the resident species,…

Populations and Evolution · Quantitative Biology 2010-05-18 Yohsuke Murase , Takashi Shimada , Nobuyasu Ito , Per Arne Rikvold

Motivated by the wide range of known self-replicating systems, some far from genetics, we study a system composed by individuals having an internal dynamics with many possible states that are partially stable, with varying mutation rates.…

Biological Physics · Physics 2015-10-07 Tommaso Brotto , Guy Bunin , Jorge Kurchan

Aging is thought to be a consequence of intrinsic breakdowns in how genetic information is processed. But mounting experimental evidence suggests that aging can be slowed. To help resolve this mystery, I derive a mortality equation which…

Populations and Evolution · Quantitative Biology 2022-09-01 Thomas Fink

We study the evolutionary dynamics of a phenotypically structured population in a changing environment , where the environmental conditions vary with a linear trend but in an oscillatory manner. Such phenomena can be described by parabolic…

Analysis of PDEs · Mathematics 2021-05-04 Susely Figueroa Iglesias , Sepideh Mirrahimi

We study the dynamics of phenotypically structured populations in environments with fluctuations. In particular, using novel arguments from the theories of Hamilton-Jacobi equations with constraints and homogenization, we obtain results…

Analysis of PDEs · Mathematics 2013-06-04 Sepideh Mirrahimi , Benoit Perthame , Panagiotis E. Souganidis

Genetic data are often used to infer demographic history and changes or detect genes under selection. Inferential methods are commonly based on models making various strong assumptions: demography and population structures are supposed…

Populations and Evolution · Quantitative Biology 2020-07-28 Clotilde Lepers , Sylvain Billiard , Matthieu Porte , Sylvie Méléard , Viet Chi Tran

We introduce an age-structured asexual population model containing all the relevant features of evolutionary ageing theories. Beneficial as well as deleterious mutations, heredity and arbitrary fecundity are present and managed by natural…

Statistical Mechanics · Physics 2009-10-31 R. N. Onody , N. G. F. de Medeiros

We address a novel approach for stochastic individual-based modelling of a single species population. Individuals are distinguished by their remaining lifetimes, which are regulated by the interplay between the inexorable running of time…

Populations and Evolution · Quantitative Biology 2021-01-08 Luis R. T. Neves , Leonardo Paulo Maia

We model and study the genetic evolution and conservation of a population of diploid hermaphroditic organisms, evolving continuously in time and subject to resource competition. In the absence of mutations, the population follows a 3-type…

Probability · Mathematics 2012-07-23 Camille Coron

Phenotypic evolution implies sequential fixations of new genomic sequences. The speed at which these mutations fixate depends, in part, on the relative fitness (selection coefficient) of the mutant vs. the ancestor. Using a simple…

Populations and Evolution · Quantitative Biology 2014-02-04 Sorin Tanase-Nicola , Ilya Nemenman
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