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We study the thermodynamic behavior of a simple off-lattice model for protein folding. The model is two-dimensional and has two different ``amino acids''. Using numerical simulations of all chains containing eight or ten monomers, we…

chem-ph · Physics 2009-10-28 Anders Irbäck , Frank Potthast

Acid solutions exhibit a variety of complex structural and dynamical features arising from the presence of multiple interacting reactive proton defects and counterions. However, disentangling the transient structural motifs of proton…

Chemical Physics · Physics 2018-05-09 Joseph A. Napoli , Ondrej Marsalek , Thomas E. Markland

Using density functional theory the atomic and electronic structure of sodium are predicted to depart substantially from those expected of simple metals for $r_s <$ 2.48 ($p > 130$ GPa). Newly-predicted phases include those with low…

Materials Science · Physics 2009-10-31 J. B. Neaton , N. W. Ashcroft

We report a molecular dynamics simulation of selenium, described by a three-body interaction. The temperatures T_g and T_c and the structural properties are in agreement with experiment. The mean nearest neighbor coordination number is 2.1.…

Disordered Systems and Neural Networks · Physics 2009-10-31 D. Caprion , H. R. Schober

The solvent quality determines the collapsed or the expanded state of a polymer. For example, a polymer dissolved in a poor solvent collapses, whereas in a good solvent it opens up. While this standard understanding is generally valid,…

Soft Condensed Matter · Physics 2020-07-01 Yani Zhao , Manjesh K. Singh , Kurt Kremer , Robinson Cortes-Huerto , Debashish Mukherji

In this study, a possible non-quasiparticle glue for superconductivity of both conventional and unconventional superconductors is explored in a pure electron picture. It is shown clearly that the moving electrons due to the electromagnetic…

Superconductivity · Physics 2009-09-04 X. Q. Huang

Combining the principal component analysis (PCA) of X-ray spectrum with MD simulations, we experimentally reveal the existence of three basic components in water. These components exhibit distinct structures, densities, and temperature…

Soft Condensed Matter · Physics 2022-10-13 Zhipeng Jin , Jiangtao Zhao , Gang Chen , Guo Chen , Zhenlin Luo , Lei Xu

We combine small angle scattering experiments and simulations to investigate the internal structure and interactions of composite Poly(N-isopropylacrylamide)-Poly(ethylene glycol) (PNIPAM-PEG) microgels. At low temperatures the…

We study the relation between $\alpha$-helix formation and folding for a simple artificial peptide, Ala$_{10}$-Gly$_5$-Ala$_{10}$. Our data rely on multicanonical Monte Carlo simulations where the interactions among all atoms are taken into…

Statistical Mechanics · Physics 2009-11-07 Nelson A. Alves , Ulrich H. E. Hansmann

We consider a fluid of hard spheres bearing one or two uniform circular adhesive patches, distributed so as not to overlap. Two spheres interact via a ``sticky'' Baxter potential if the line joining the centers of the two spheres intersects…

Statistical Mechanics · Physics 2009-11-13 Riccardo Fantoni , Domenico Gazzillo , Achille Giacometti , Mark A. Miller , Giorgio Pastore

We examine five different popular rigid water models (SPC, SPCE, TIP3P, TIP4P and TIP5P) using MD simulations in order to investigate the hydrophobic hydration and interaction of apolar Lennard-Jones solutes as a function of temperature in…

Soft Condensed Matter · Physics 2009-09-29 Dietmar Paschek

The interplay of nematic order and phase separation in solutions of semiflexible polymers in solvents of variable quality is investigated by density functional theory (DFT) and molecular dynamics (MD) simulations. We studied coarse-grained…

Soft Condensed Matter · Physics 2019-09-04 Jiarul Midya , Sergei A. Egorov , Kurt Binder , Arash Nikoubashman

Semiflexible polymers are widely used as a paradigm for understanding structural phases in biomolecules including folding of proteins. Here, we compare bead-spring and bead-stick variants of coarse-grained semiflexible polymer models that…

Soft Condensed Matter · Physics 2024-02-16 Wolfhard Janke , Suman Majumder , Martin Marenz , Subhajit Paul

We present a study of the solvation properties of model aqueous electrode interfaces. The exposed electrodes we study strongly bind water and have closed packed crystalline surfaces, which template an ordered water adlayer adjacent to the…

Statistical Mechanics · Physics 2015-06-11 David T. Limmer , Adam P. Willard , Paul A. Madden , David Chandler

Based on a newly developed contact-density chain-growth algorithm, we have simulated a nongrafted peptide in the vicinity of different attractive substrates. We analyzed the specificity of the peptide adsorption by focussing on the…

Soft Condensed Matter · Physics 2007-10-24 Michael Bachmann , Wolfhard Janke

The mechanics of complex soft matter often cannot be understood in the classical physical frame of flexible polymers or rigid rods. The underlying constituents are semiflexible polymers, whose finite bending stiffness ($\kappa$) leads to…

The aqueous solvent profoundly influences protein folding, yet its effects are relatively poorly understood. In this study, we investigate the impact of solvation on the folding of lattice proteins by using Monte Carlo simulations. The…

Soft Condensed Matter · Physics 2025-04-01 Nhung T. T. Nguyen , Pham Nam Phong , Duy Manh Le , Minh-Tien Tran , Trinh Xuan Hoang

We present the results of a molecular dynamics simulation study of thermodynamic and structural properties upon supercooling of a low concentration sodium chloride solution in TIP4P water and the comparison with the corresponding bulk…

Soft Condensed Matter · Physics 2008-06-25 D. Corradini , P. Gallo , M. Rovere

Using molecular dynamics simulations we study the thermodynamic behavior of a single-component covalent material described by the recently proposed Environment-Dependent Interatomic Potential (EDIP). The parameterization of EDIP for silicon…

Materials Science · Physics 2009-11-07 P. Keblinski , M. Z. Bazant , R. K. Dash , M. M. Treacy

Synthetic copolymers and biopolymers, such as polypeptides and double-stranded DNA, often exhibit strong variations in bending stiffness along their contour, which can significantly impact conformational behavior at larger scales. To…

Soft Condensed Matter · Physics 2025-11-04 Yannick Witzky , Friederike Schmid , Arash Nikoubashman