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Related papers: Cantilever-Based Biosensors in CMOS Technology

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Solid-state nanopores, nm-sized holes in thin, freestanding membranes, are powerful single-molecule sensors capable of interrogating a wide range of target analytes, from small molecules to large polymers. Interestingly, due to their high…

Microfluidics offer remarkable flexibility for in-flow analyte characterization and can even measure the mechanical properties of biological cells through the application of hydrodynamic forces. In this work, we present a new approach to…

Soft Condensed Matter · Physics 2025-01-22 Alberto Martin-Perez , Daniel Ramos

Mechanical cantilevers are central to nanotechnology, with ultimate sensitivity achieved at the atomic limit, where low bending rigidity makes stability the fundamental challenge. Here, we introduce a wrinkle-induced stiffening approach…

Mesoscale and Nanoscale Physics · Physics 2025-08-25 Hadi Arjmandi-Tash , Roshan Prasad , Hanqing Liu , Gerard Verbiest , Dominic Vella , Farbod Alijani

Microtubules (MTs) are important cytoskeletal structures, engaged in a number of specific cellular activities, including vesicular traffic, cell cyto-architecture and motility, cell division, and information processing within neuronal…

Subcellular Processes · Quantitative Biology 2007-05-23 Avner Priel , Arnolt J. Ramos , Jack A. Tuszynski , Horacio F. Cantiello

The quantum sensing landscape has been revolutionized by advanced technologies like superconducting circuits and qubit-based systems which have furthered the ability to probe and understand fundamental properties of quantum matter. Here, we…

Quantum Physics · Physics 2025-10-02 Ioannis Petrides , Arpit Arora , Prineha Narang

We report on the design, fabrication, and implementation of ultrasensitive micromechanical oscillators. Our ultrathin single-crystal silicon cantilevers with integrated magnetic structures are the first of their kind: They are fabricated…

Mesoscale and Nanoscale Physics · Physics 2007-05-23 Michelle D. Chabot , John M. Moreland , Lan Gao , Sy-Hwang Liou , Casey W. Miller

The operation of solid-state qubits often relies on single-shot readout using a nanoelectronic charge sensor, and the detection of events in a noisy sensor signal is crucial for high fidelity readout of such qubits. The most common…

Mesoscale and Nanoscale Physics · Physics 2015-06-09 J. R. Prance , B. J. Van Bael , C. B. Simmons , D. E. Savage , M. G. Lagally , Mark Friesen , S. N. Coppersmith , M. A. Eriksson

Biomedical and environmental testing currently require access to highly specialized facilities or extensive training. Current biochemical tests require complex reagents to achieve a simple human readable result such as a color change. This…

Controlled atomic scale fabrication of functional devices is one of the holy grails of nanotechnology. The most promising class of techniques that enable deterministic nanodevice fabrication are based on scanning probe patterning or surface…

A key task in the emerging field of bioelectronics is the transduction between ionic/protonic and electronic signals at high fidelity. This is a considerable challenge since the two carrier types exhibit intrinsically different physics and…

Spontaneous collapse models predict that a weak force noise acts on any mechanical system, as a consequence of the collapse of the wave function. Significant upper limits on the collapse rate have been recently inferred from precision…

Quantum Physics · Physics 2017-09-20 A. Vinante , R. Mezzena , P. Falferi , M. Carlesso , A. Bassi

Optical biosensors based on micro-/nano-fibers are highly valuable for probing and monitoring liquid environments and bioactivity. Most of current optical biosensors, however, are still based on glass, semiconductors, or metallic materials,…

Optics · Physics 2025-02-27 X. Yang , L. Xu , S. Xiong , H. Rao , F. Tan , J. Yan , Y. Bao , A. Albanese , A. Camposeo , D. Pisignano , B. Li

This paper devotes to formulating several multiscale models to study the effect of pH-dependent ionic inhomogeneity on the electrical potential distributions and the graded elastic properties of a nanoscale DNA film and the related bending…

Applied Physics · Physics 2017-06-27 Neng-Hui Zhang , Wei-Lie Meng , Cheng-Yin Zhang , Jun-Zheng Wu

An experimental arrangement and a set of experiments are developed to generate empirical evidence of the effect of noise on a rotating, macro-scale cantilever structure. The experiment is a controlled representation of a rotating machinery…

Applied Physics · Physics 2023-06-01 Lautaro Cilenti , Maria Cameron , Balakumar Balachandran

Vertical optofluidic biosensors based on refractive index sensing promise highest sensitivities at smallest area foot-print. Nevertheless, when it comes to large scale fabrication and application of such sensors, cheap and robust platforms…

This study explores the fusion of a field-effect transistor (FET), a paper-based analytical cartridge, and the computational power of deep learning (DL) for quantitative biosensing via kinetic analyses. The FET sensors address the low…

THz technologies are a powerful tool for label-free detection of biomolecules. However, significant reduction of the lower detection limit is required to apply THz-sensors in biomedical diagnosis. This paper reports an ultrasensitive…

Organic Electrochemical Transistors are considered today as a key technology to interact with biological medium through their intrinsic ionic-electronic coupling. In this paper, we show how this coupling can be finely tuned (in operando)…

Signal Processing · Electrical Eng. & Systems 2021-08-31 Mahdi Ghazal , Michel Daher Mansour , Corentin Scholaert , Thomas Dargent , Yannick Coffinier , Sebastien Pecqueur , Fabien Alibart

On-chip photodetectors are essential components in optical communications as they convert light into an electrical signal. Photobolometers are type of photodetector that functions through a resistance change caused by electronic temperature…

Optics · Physics 2023-09-27 Jacek Gosciniak

Single ion detection has, for many years, been the domain of large devices such as the Geiger counter, and studies on interactions of ionized gasses with materials have been limited to large systems. To date, there have been no reports on…

Mesoscale and Nanoscale Physics · Physics 2015-07-14 Adam W. Bushmaker , Vanessa Oklejas , Don Walker , Alan R. Hopkins , Jihan Chen , Stephen B. Cronin