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Cryo-electron microscopy (cryo-EM) emerges as a pivotal technology for determining the architecture of cells, viruses, and protein assemblies at near-atomic resolution. Traditional particle picking, a key step in cryo-EM, struggles with…

Biomolecules · Quantitative Biology 2024-04-17 Chentianye Xu , Xueying Zhan , Min Xu

In this study, we consider a continuous min--max optimization problem $\min_{x \in \mathbb{X} \max_{y \in \mathbb{Y}}}f(x,y)$ whose objective function is a black-box. We propose a novel approach to minimize the worst-case objective function…

Neural and Evolutionary Computing · Computer Science 2023-03-29 Atsuhiro Miyagi , Yoshiki Miyauchi , Atsuo Maki , Kazuto Fukuchi , Jun Sakuma , Youhei Akimoto

The thermodynamic evolution of Coronal Mass Ejections (CMEs) in the inner corona (< 1.5 R$_{sun}$) is not yet completely understood. In this work, we study the evolution of thermodynamic properties of a CME core observed in the inner corona…

Solar and Stellar Astrophysics · Physics 2023-01-31 Jyoti Sheoran , Vaibhav Pant , Ritesh Patel , Dipankar Banerjee

Column chromatography is a laboratory and industrial technique used to separate different substances mixed in a solution. Mathematically, it can be modelled using non-linear partial differential equations whose main ingredients are the…

Numerical Analysis · Mathematics 2024-05-16 R. Donat , M. C. Martí , P. Mulet

Estimating physical properties of galaxies from wide-field surveys remains a central challenge in astrophysics. While spectroscopy provides precise measurements, it is observationally expensive, and photometry discards morphological…

Instrumentation and Methods for Astrophysics · Physics 2025-12-05 Mikaeel Yunus , John F. Wu , Benne W. Holwerda

In this study, we analyze behaviours of the well-known CMA-ES by extracting the time-series features on its dynamic strategy parameters. An extensive experiment was conducted on twelve CMA-ES variants and 24 test problems taken from the…

Neural and Evolutionary Computing · Computer Science 2021-04-19 Jacob de Nobel , Hao Wang , Thomas Bäck

Using a coarse molecular-dynamics (CMD) approach with an appropriate choice of coarse variable (order parameter), we map the underlying effective free-energy landscape for the melting of a crystalline solid. Implementation of this approach…

Materials Science · Physics 2009-11-11 Miguel A. Amat , Ioannis G. Kevrekidis , Dimitrios Maroudas

Graph coloring is a challenging combinatorial optimization problem with a wide range of applications. In this paper, a distribution evolutionary algorithm based on a population of probability model (DEA-PPM) is developed to address it…

Neural and Evolutionary Computing · Computer Science 2023-05-03 Yongjian Xu , Huabin Cheng , Ning Xu , Yu Chen , Chengwang Xie

We consider the identification of heterogeneous linear elastic moduli in the context of time-harmonic elastodynamics. This inverse problem is formulated as the minimization of the modified error in constitutive equation (MECE), an…

Analysis of PDEs · Mathematics 2018-12-11 Wilkins Aquino , Marc Bonnet

One of the most promising applications of near-term quantum computing is the simulation of quantum systems, a classically intractable task. Quantum simulation requires computationally expensive matrix exponentiation; Trotter-Suzuki…

Neural and Evolutionary Computing · Computer Science 2019-04-24 Benjamin D. M. Jones , George O. O'Brien , David R. White , Earl T. Campbell , John A. Clark

Multimodal optimization requires both exploration and exploitation. Exploration identifies promising attraction basins, while exploitation finds the best solutions within these basins. The balance between exploration and exploitation can be…

Neural and Evolutionary Computing · Computer Science 2025-06-03 Chandula Fernando , Kushani De Silva

The nature of diffusion is usually studied for particles or time-evolving systems. Similar in principle, such studies can be conducted by tracking how a given function of observable properties evolves over time-akin to the evolution of…

Statistical Mechanics · Physics 2026-03-10 M. Süzen

Active regions often show S-shaped structures in the corona called sigmoids. These are highly sheared and twisted loops formed along the polarity inversion line. They are considered to be one of the best pre-eruption signatures for CMEs.…

Solar and Stellar Astrophysics · Physics 2021-03-31 Sargam M. Mulay , Durgesh Tripathi , Helen Mason

Evolution Strategies such as CMA-ES (covariance matrix adaptation evolution strategy) and NES (natural evolution strategy) have been widely used in machine learning applications, where an objective function is optimized without using its…

Optimization and Control · Mathematics 2019-10-28 Haishan Ye , Tong Zhang

Recently it was shown by Nesterov (2011) that techniques form convex optimization can be used to successfully accelerate simple derivative-free randomized optimization methods. The appeal of those schemes lies in their low complexity, which…

Optimization and Control · Mathematics 2014-06-13 Sebastian U. Stich

Determining the 3D structures of biological molecules is a key problem for both biology and medicine. Electron Cryomicroscopy (Cryo-EM) is a promising technique for structure estimation which relies heavily on computational methods to…

Machine Learning · Statistics 2015-01-29 Ali Punjani , Marcus A. Brubaker

The random motion of molecules in living cells has consistently been reported to deviate from standard Brownian motion, a behavior coined as ``anomalous diffusion''. Fluorescence Correlation Spectroscopy (FCS) is a powerful method to…

Quantitative Methods · Quantitative Biology 2024-07-18 Nathan Quiblier , Jan-Michael Rye , Pierre Leclerc , Henri Truong , Abdelkrim Hannou , Laurent Héliot , Hugues Berry

This paper presents an efficient method based on Evolutionary Center Algorithm (ECA) for accurately and efficiently determining the optimal reaction and diffusion parameters for Chemical-Diffusive Models (CDM) to simulate flame acceleration…

Chemical Physics · Physics 2026-04-23 Huahua Xiao , Xu Zhang , Mingbin Zhao , Congling Shi

This paper introduces an accurate edge-based smoothed finite element method (ES-FEM) for electromagnetic analysis for both two dimensional cylindrical and three dimensional cartesian systems, which shows much better performance in terms of…

Computational Engineering, Finance, and Science · Computer Science 2019-10-30 Yangfan Zhang , Pengfei Wang , Wenping Li , Shunchuan Yang

In this paper, an evolutionary strategy (ES) method is introduced as an optimization approach to solve problems in the manufacturing area. The ES method is applied to a case study for milling operations. The results show that it can…

Optimization and Control · Mathematics 2015-01-08 Zhixin Yang
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