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An important challenge in interactive machine learning, particularly in subjective or ambiguous domains, is fostering bi-directional alignment between humans and models. Users teach models their concept definition through data labeling,…

Human-Computer Interaction · Computer Science 2025-04-14 Simret Araya Gebreegziabher , Yukun Yang , Elena L. Glassman , Toby Jia-Jun Li

Digital pathology has emerged as a transformative approach to tissue analysis, offering unprecedented opportunities for objective, quantitative assessment of histopathological features. However, the complexity of implementing artificial…

Quantitative Methods · Quantitative Biology 2025-09-17 Noor Shaker , Mohamed AbouZleikha , Nuha Shaker

The visual analysis of retinal data contributes to the understanding of a wide range of eye diseases. For the evaluation of cross-sectional studies, ophthalmologists rely on workflows and toolsets established in their work environment. That…

Human-Computer Interaction · Computer Science 2023-01-06 Martin Röhlig , Lars Nonnemann , Hans-Jörg Schulz , Oliver Stachs , Heidrun Schumann

Tissue microarray (TMA) images have been used increasingly often in cancer studies and the validation of biomarkers. TACOMA---a cutting-edge automatic scoring algorithm for TMA images---is comparable to pathologists in terms of accuracy and…

Computer Vision and Pattern Recognition · Computer Science 2018-12-04 Donghui Yan , Timothy W. Randolph , Jian Zou , Peng Gong

Interest in sustainability information has surged in recent years. However, the data required for a life cycle assessment (LCA) that maps the materials and processes from product manufacturing to disposal into environmental impacts (EI) are…

Complex prediction models such as deep learning are the output from fitting machine learning, neural networks, or AI models to a set of training data. These are now standard tools in science. A key challenge with the current generation of…

Machine Learning · Computer Science 2022-10-21 Meng Liu , Tamal K. Dey , David F. Gleich

This paper introduces new methodology based on the field of Topological Data Analysis for detecting anomalies in multivariate time series, that aims to detect global changes in the dependency structure between channels. The proposed…

Statistics Theory · Mathematics 2024-06-11 Frédéric Chazal , Martin Royer , Clément Levrard

One of the greatest research challenges of this century is to understand the neural basis for how behavior emerges in brain-body-environment systems. To this end, research has flourished along several directions but have predominantly…

Neurons and Cognition · Quantitative Biology 2021-06-10 Madhavun Candadai

The analysis of a protein-expression pattern from tissue microarray (TMA) data will not immediately give an answer on synergistic or antagonistic effects between the expression of the observed proteins. But contrary to apparent first…

Molecular Networks · Quantitative Biology 2018-03-07 H Buerger , F Boecker , J Packeisen , K Agelopoulos , K Poos , W Nadler , E Korsching

This book dwells on mathematical and algorithmic issues of data analysis based on generality order of descriptions and respective precision. To speak of these topics correctly, we have to go some way getting acquainted with the important…

Logic in Computer Science · Computer Science 2019-08-30 Sergei O. Kuznetsov

Scientists often use observational time series data to study complex natural processes, but regression analyses often assume simplistic dynamics. Recent advances in deep learning have yielded startling improvements to the performance of…

Machine Learning · Computer Science 2023-04-21 Cory Shain , William Schuler

This paper presents a complete explainable system that interprets a set of data, abstracts the underlying features and describes them in a natural language of choice. The system relies on two crucial stages: (i) identifying emerging…

Logic in Computer Science · Computer Science 2025-02-14 Flavio Bertini , Alessandro Dal Palù , Federica Zaglio , Francesco Fabiano , Andrea Formisano

This paper presents TIRA, a Matlab library gathering several methods for the computation of interval over-approximations of the reachable sets for both continuous- and discrete-time nonlinear systems. Unlike other existing tools, the main…

Systems and Control · Computer Science 2019-02-15 Pierre-Jean Meyer , Alex Devonport , Murat Arcak

Deep learning has achieved great success in a wide spectrum of multimedia applications such as image classification, natural language processing and multimodal data analysis. Recent years have seen the development of many deep learning…

Machine Learning · Computer Science 2021-08-06 Naili Xing , Sai Ho Yeung , Chenghao Cai , Teck Khim Ng , Wei Wang , Kaiyuan Yang , Nan Yang , Meihui Zhang , Gang Chen , Beng Chin Ooi

Modern biomedical applications often involve time-series data, from high-throughput phenotyping of model organisms, through to individual disease diagnosis and treatment using biomedical data streams. Data and tools for time-series analysis…

Databases · Computer Science 2019-05-06 Ben D. Fulcher , Carl H. Lubba , Sarab S. Sethi , Nick S. Jones

Artificial Intelligence (AI), and in particular, the explainability thereof, has gained phenomenal attention over the last few years. Whilst we usually do not question the decision-making process of these systems in situations where only…

Artificial Intelligence · Computer Science 2021-01-29 Iena Petronella Derks , Alta de Waal

The current bulk materials discovery cycle has several inefficiencies from initial computational predictions through fabrication and analyses. Materials are generally evaluated in a singular fashion, relying largely on human-driven…

Materials Science · Physics 2021-02-12 Olivia F. Dippo , Kevin R. Kaufmann , Kenneth S. Vecchio

In recent years, training data attribution (TDA) methods have emerged as a promising direction for the interpretability of neural networks. While research around TDA is thriving, limited effort has been dedicated to the evaluation of…

Computer-based assessments routinely generate detailed interaction logs -- commonly referred to as process data -- that record every action a respondent performs during task completion, yet systematic preprocessing guidance, integrated…

Applications · Statistics 2026-04-21 Daeun Hwangbo , Junyeong Park , Minjeong Jeon , Ick Hoon Jin

In biological research machine learning algorithms are part of nearly every analytical process. They are used to identify new insights into biological phenomena, interpret data, provide molecular diagnosis for diseases and develop…