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In sexual population, recombination reshuffles genetic variation and produces novel combinations of existing alleles, while selection amplifies the fittest genotypes in the population. If recombination is more rapid than selection,…

Populations and Evolution · Quantitative Biology 2015-06-05 Richard A. Neher , Marija Vucelja , Marc Mézard , Boris I. Shraiman

An elementary biostatistical theory based on a selectivity-variability principle is proposed to address a question raised by Charles Darwin, namely, how one sex of a sexually dimorphic species might tend to evolve with greater variability…

Populations and Evolution · Quantitative Biology 2024-10-04 Theodore P. Hill

In evolutionary algorithms, the fitness of a population increases with time by mutating and recombining individuals and by a biased selection of more fit individuals. The right selection pressure is critical in ensuring sufficient…

Artificial Intelligence · Computer Science 2007-05-23 Marcus Hutter

This work presents a population genetic model of evolution, which includes haploid selection, mutation, recombination, and drift. The mutation-selection equilibrium can be expressed exactly in closed form for arbitrary fitness functions…

Populations and Evolution · Quantitative Biology 2023-02-28 Jenny M. Poulton , Lee Altenberg , Chris Watkins

How fast does a population evolve from one fitness peak to another? We study the dynamics of evolving, asexually reproducing populations in which a certain number of mutations jointly confer a fitness advantage. We consider the time until a…

Populations and Evolution · Quantitative Biology 2010-03-31 Chaitanya S. Gokhale , Yoh Iwasa , Martin A. Nowak , Arne Traulsen

We consider a nonlinear structured population model with a distributed recruitment term. The question of the existence of non-trivial steady states can be treated (at least!) in three different ways. One approach is to study spectral…

Populations and Evolution · Quantitative Biology 2019-03-06 Azmy S. Ackleh , Jozsef Z. Farkas

A general procedure to formulate asexual (unstructured, deterministic) population dynamical models resulting from individual pairwise interactions is proposed. Individuals are characterized by a continuous strategy that represents all their…

Populations and Evolution · Quantitative Biology 2014-11-04 Fabio Dercole

The two-parent reproduction model of Derrida and Peliti is simulated on a rugged fitness landscape. Fixed fitness values for each possible genotype are assigned randomly, with all fit individuals having the same probability of reproduction.…

adap-org · Physics 2015-06-30 Jan Finjord

We study a stochastic spatial model of biological competition in which two species have the same birth and death rates, but different diffusion constants. In the absence of this difference, the model can be considered as an off-lattice…

Populations and Evolution · Quantitative Biology 2015-06-16 Simone Pigolotti , Roberto Benzi

When beneficial mutations are relatively common, competition between multiple unfixed mutations can reduce the rate of fixation in well-mixed asexual populations. We introduce a one dimensional model with a steady accumulation of beneficial…

Populations and Evolution · Quantitative Biology 2013-02-19 Jakub Otwinowski , Stefan Boettcher

How self-incompatibility systems are maintained in plant populations is still a debated issue. Theoretical models predict that self-incompatibility systems break down according to the intensity of inbreeding depression and number of…

Populations and Evolution · Quantitative Biology 2012-02-02 Miguel Navascués , Solenn Stoeckel , Stephanie Mariette

We consider a fitness-structured population model with competition and migration between nearest neighbors. Under a combination of large population and rare migration limits we are particularly interested in the asymptotic behavior of the…

Probability · Mathematics 2012-07-20 Anton Bovier , Shi-Dong Wang

This is an introductory review of deterministic mutation-selection models for asexual populations (i.e., quasispecies theory) and related topics. First, the basic concepts of fitness, mutations, and sequence space are introduced. Different…

Populations and Evolution · Quantitative Biology 2007-07-26 Kavita Jain , Joachim Krug

Resource are often not uniformly distributed within a population. Spatial variations of concentration of a resource, change the fitness of competing strategies locally. The notion of fitness varying with respect to both genotype and…

Populations and Evolution · Quantitative Biology 2022-04-08 Hossein Nemati , Mohammad Reza Ejtehadi , Kamran Kaveh

Cycling tissues such as the intestinal epithelium, germ line, and hair follicles, require a constant flux of differentiated cells. These tissues are maintained by a population of stem cells, which generate differentiated progenies and…

Cell Behavior · Quantitative Biology 2013-05-20 Sahand Hormoz

The growing probabilities of additional offspring with the beneficial reversal allele for various population sizes, $N$, sequence lengths, $L$, selective advantages, $s$, fitness parameters, $k$, and measuring parameters, $C$, were…

Populations and Evolution · Quantitative Biology 2016-05-25 Wonpyong Gill

In sexual populations, selection operates neither on the whole genome, which is repeatedly taken apart and reassembled by recombination, nor on individual alleles that are tightly linked to the chromosomal neighborhood. The resulting…

Populations and Evolution · Quantitative Biology 2014-03-25 Richard A. Neher , Taylor A. Kessinger , Boris I. Shraiman

This paper is concerned with the evolution of haploid organisms that reproduce asexually. In a seminal piece of work, Eigen and coauthors proposed the quasispecies model in an attempt to understand such an evolutionary process. Their work…

Populations and Evolution · Quantitative Biology 2012-03-07 Narendra M. Dixit , Piyush Srivastava , Nisheeth K. Vishnoi

I study a population model in which the reproduction rate lambda is inherited with mutation, favoring fast reproducers in the short term, but conflicting with a process that eliminates agglomerations of individuals. The model is a variant…

Statistical Mechanics · Physics 2021-06-02 Ronald Dickman

We find that the hypothesis made by Jan, Stauffer and Moseley [Theory in Biosc., 119, 166 (2000)] for the evolution of sex, namely a strategy devised to escape extinction due to too many deleterious mutations, is sufficient but not…

Soft Condensed Matter · Physics 2009-11-07 Erkan Tuzel , Volkan Sevim , Ayse Erzan
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