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The advent of data science has spurred interest in estimating properties of distributions over large alphabets. Fundamental symmetric properties such as support size, support coverage, entropy, and proximity to uniformity, received most…

Information Theory · Computer Science 2016-11-29 Jayadev Acharya , Hirakendu Das , Alon Orlitsky , Ananda Theertha Suresh

Membrane proteins deform the surrounding lipid bilayer, which can lead to membrane-mediated interactions between neighboring proteins. Using the mechanosensitive channel of large conductance (MscL) as a model system, we demonstrate how the…

Biomolecules · Quantitative Biology 2016-11-03 Osman Kahraman , William S. Klug , Christoph A. Haselwandter

We consider multivariate two-sample tests of means, where the location shift between the two populations is expected to be related to a known graph structure. An important application of such tests is the detection of differentially…

Applications · Statistics 2012-07-02 Laurent Jacob , Pierre Neuvial , Sandrine Dudoit

Deep neural networks (DNN) have been deployed in many software systems to assist in various classification tasks. In company with the fantastic effectiveness in classification, DNNs could also exhibit incorrect behaviors and result in…

Software Engineering · Computer Science 2020-06-16 Yang Feng , Qingkai Shi , Xinyu Gao , Jun Wan , Chunrong Fang , Zhenyu Chen

3' untranslated regions (3' UTRs) contain binding sites for many regulatory elements, and in particular for microRNAs (miRNAs). The importance of miRNA-mediated post-transcriptional regulation has become increasingly clear in the last few…

Genomics · Quantitative Biology 2007-07-17 Davide Cora , Ferdinando Di Cunto , Michele Caselle , Paolo Provero

The tools and technology that are currently used to analyze chemical compound structures that identify polymer types in microplastics are not well-calibrated for environmentally weathered microplastics. Microplastics that have been degraded…

Machine Learning · Computer Science 2025-01-09 Sheela Ramanna , Danila Morozovskii , Sam Swanson , Jennifer Bruneau

Explainable artificial intelligence (XAI) approaches have been increasingly applied in drug discovery to learn molecular representations and identify substructures driving property predictions. However, building end-to-end explainable…

Machine Learning · Computer Science 2026-05-29 Zanyu Shi , Yang Wang , Pathum Weerawarna , Jie Zhang , Timothy Richardson , Yijie Wang , Kun Huang

Quantum Machine Learning (QML) continues to evolve, unlocking new opportunities for diverse applications. In this study, we investigate and evaluate the applicability of QML models for binary classification of genome sequence data by…

Machine Learning · Computer Science 2025-01-15 Navneet Singh , Shiva Raj Pokhrel

One of the objectives of designing feature selection learning algorithms is to obtain classifiers that depend on a small number of attributes and have verifiable future performance guarantees. There are few, if any, approaches that…

Machine Learning · Computer Science 2010-05-05 Mohak Shah , Mario Marchand , Jacques Corbeil

Graph neural networks have recently become a standard method for analysing chemical compounds. In the field of molecular property prediction, the emphasis is now put on designing new model architectures, and the importance of atom…

Chemical Physics · Physics 2021-02-15 Agnieszka Pocha , Tomasz Danel , Łukasz Maziarka

The latest biological findings observe that the traditional motionless 'lock-and-key' theory is not generally applicable because the receptor and ligand are constantly moving. Nonetheless, remarkable changes in associated atomic sites and…

Computational Engineering, Finance, and Science · Computer Science 2023-11-01 Fang Wu , Shuting Jin , Yinghui Jiang , Xurui Jin , Bowen Tang , Zhangming Niu , Xiangrong Liu , Qiang Zhang , Xiangxiang Zeng , Stan Z. Li

For the last few decades, optimization has been developing at a fast rate. Bio-inspired optimization algorithms are metaheuristics inspired by nature. These algorithms have been applied to solve different problems in engineering, economics,…

Artificial Intelligence · Computer Science 2014-07-17 Muhammad Marwan Muhammad Fuad

Gene expression analysis aims at identifying the genes able to accurately predict biological parameters like, for example, disease subtyping or progression. While accurate prediction can be achieved by means of many different techniques,…

Methodology · Statistics 2008-09-11 Christine De Mol , Sofia Mosci , Magali Traskine , Alessandro Verri

Probing techniques have shown promise in revealing how LLMs encode human-interpretable concepts, particularly when applied to curated datasets. However, the factors governing a dataset's suitability for effective probe training are not…

Artificial Intelligence · Computer Science 2025-05-27 Yongjie Wang , Yibo Wang , Xin Zhou , Zhiqi Shen

Generalised quantum measurements with two outcomes are fully characterised by two real parameters, dubbed as sharpness parameter and biasedness parameter and they can be linked with different aspects of the experimental setup. It is known…

Quantum Physics · Physics 2018-04-04 Debarshi Das , Shiladitya Mal , Dipankar Home

Spectroscopies utilizing free electron beams as probes offer detailed information on the reciprocal-space excitations of 2D materials such as graphene and transition metal dichalcogenide monolayers. Yet, despite the attention paid to such…

Materials Science · Physics 2024-02-08 Andrew W. Rossi , Marc R. Bourgeois , Caleb Walton , David J. Masiello

This article studies the asymptotic behaviors of nonparametric estimators of two overlapping measures, namely Pianka's and MacArthur-Levins measures. The plug-in principle and the method of kernel density estimation are used to estimate…

Statistics Theory · Mathematics 2020-11-25 Tareq Alodat , M. T. Alodat , Dareen Omari

The recent success of graph neural networks has significantly boosted molecular property prediction, advancing activities such as drug discovery. The existing deep neural network methods usually require large training dataset for each…

Machine Learning · Computer Science 2021-02-17 Zhichun Guo , Chuxu Zhang , Wenhao Yu , John Herr , Olaf Wiest , Meng Jiang , Nitesh V. Chawla

Schema matching is the process of identifying correspondences between the elements of two given schemata, essential for database management systems, data integration, and data warehousing. For datasets across different scenarios, the…

Databases · Computer Science 2025-03-07 Longyu Feng , Huahang Li , Chen Jason Zhang

The statistical characterization of the measurement errors of a phasor measurement unit (PMU) is currently receiving considerable interest in the power systems community. This paper focuses on the characteristics of the errors in magnitude…

Systems and Control · Electrical Eng. & Systems 2021-03-18 Demetra Salls , Jairo Ramírez Torres , Antos Cheeramban Varghese , John Patterson , Anamitra Pal