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High performance packet classification is a key component to support scalable network applications like firewalls, intrusion detection, and differentiated services. With ever increasing in the line-rate in core networks, it becomes a great…

Networking and Internet Architecture · Computer Science 2022-05-19 Hasibul Jamil , Ning Weng

Gene annotation has traditionally required direct comparison of DNA sequences between an unknown gene and a database of known ones using string comparison methods. However, these methods do not provide useful information when a gene does…

Machine Learning · Computer Science 2019-09-17 James K. Senter , Taylor M. Royalty , Andrew D. Steen , Amir Sadovnik

Acquiring genomes at single-cell resolution has many applications such as in the study of microbiota. However, deep sequencing and assembly of all of millions of cells in a sample is prohibitively costly. A property that can come to rescue…

Genomics · Quantitative Biology 2014-04-29 Zeinab Taghavi

Clustering is a commonly used method for exploring and analysing data where the primary objective is to categorise observations into similar clusters. In recent decades, several algorithms and methods have been developed for analysing…

Machine Learning · Computer Science 2021-02-17 Bryar A. Hassan , Tarik A. Rashid

While modern biotechnologies allow synthesizing new proteins and function measurements at scale, efficiently exploring a protein sequence space and engineering it remains a daunting task due to the vast sequence space of any given protein.…

Biomolecules · Quantitative Biology 2024-01-15 Jiahao Qiu , Hui Yuan , Jinghong Zhang , Wentao Chen , Huazheng Wang , Mengdi Wang

Insects comprise millions of species, many experiencing severe population declines under environmental and habitat changes. High-throughput approaches are crucial for accelerating our understanding of insect diversity, with DNA barcoding…

Counterfeiting poses a significant challenge across multiple industries, leading to financial losses and health risks. While DNA-based molecular tagging has emerged as a promising anti-counterfeiting strategy, existing methods rely on…

Cryptography and Security · Computer Science 2025-03-07 Ali Tafazoli Yazdi , Peter Nejjar , Lena Hochrein

Machine learning has proved to be a useful tool for extracting knowledge from scientific data in numerous research fields, including astrophysics, genomics, and molecular dynamics. Often, data sets from these research areas need to be…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-04-21 Javier Álvarez Cid-Fuentes , Pol Álvarez , Salvi Solà , Kuninori Ishii , Rafael K. Morizawa , Rosa M. Badia

DNA is a leading candidate as the next archival storage media due to its density, durability and sustainability. To read (and write) data DNA storage exploits technology that has been developed over decades to sequence naturally occurring…

Emerging Technologies · Computer Science 2022-05-12 Jasmine Quah , Omer Sella , Thomas Heinis

MultiGrain is a network architecture producing compact vector representations that are suited both for image classification and particular object retrieval. It builds on a standard classification trunk. The top of the network produces an…

Computer Vision and Pattern Recognition · Computer Science 2019-04-04 Maxim Berman , Hervé Jégou , Andrea Vedaldi , Iasonas Kokkinos , Matthijs Douze

Large biological datasets are being produced at a rapid pace and create substantial storage challenges, particularly in the domain of high-throughput sequencing (HTS). Most approaches currently used to store HTS data are either unable to…

Quantitative Methods · Quantitative Biology 2014-03-05 Fabien Campagne , Kevin C. Dorff , Nyasha Chambwe , James T. Robinson , Jill P. Mesirov , Thomas D. Wu

Molecular dynamics simulations provide theoretical insight into the microscopic behavior of materials in condensed phase and, as a predictive tool, enable computational design of new compounds. However, because of the large temporal and…

Chemical Physics · Physics 2020-06-18 Wujie Wang , Rafael Gómez-Bombarelli

Microstructure characterisation has been greatly enhanced through the use of electron backscatter diffraction (EBSD), where rich maps are generated through analysis of the crystal phase and orientation in the scanning electron microscope…

Materials Science · Physics 2018-11-15 Vivian S Tong , Alexander J Knowles , David Dye , T Ben Britton

Diffusion models have achieved remarkable success in high-fidelity image generation but remain computationally demanding due to their multi-step denoising process and large model sizes. Although prior work improves efficiency either by…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Zongfang Liu , Shengkun Tang , Zongliang Wu , Xin Yuan , Zhiqiang Shen

An important task in microbiome studies is to test the existence of and give characterization to differences in the microbiome composition across groups of samples. Important challenges of this problem include the large within-group…

Methodology · Statistics 2019-05-07 Jialiang Mao , Yuhan Chen , Li Ma

De novo genome assembly is challenging in highly repetitive regions; however, reference-guided assemblers often suffer from bias. We propose a framework for pangenome-guided sequence assembly, which can resolve short-read data in complex…

Quantum Physics · Physics 2026-02-11 Josh Cudby , James Bonfield , Chenxi Zhou , Richard Durbin , Sergii Strelchuk

Monitoring plankton populations in situ is fundamental to preserve the aquatic ecosystem. Plankton microorganisms are in fact susceptible of minor environmental perturbations, that can reflect into consequent morphological and dynamical…

Computer Vision and Pattern Recognition · Computer Science 2022-09-15 Paolo Didier Alfano , Marco Rando , Marco Letizia , Francesca Odone , Lorenzo Rosasco , Vito Paolo Pastore

We establish a broad methodological foundation for mixed-integer optimization with learned constraints. We propose an end-to-end pipeline for data-driven decision making in which constraints and objectives are directly learned from data…

Optimization and Control · Mathematics 2023-10-30 Donato Maragno , Holly Wiberg , Dimitris Bertsimas , S. Ilker Birbil , Dick den Hertog , Adejuyigbe Fajemisin

Heterogeneous information networks(HINs) become popular in recent years for its strong capability of modelling objects with abundant information using explicit network structure. Network embedding has been proved as an effective method to…

Machine Learning · Computer Science 2021-04-12 Xinyi Zhang , Lihui Chen

Motivation: The comparison of diverse genomic datasets is fundamental to understanding genome biology. Researchers must explore many large datasets of genome intervals (e.g., genes, sequence alignments) to place their experimental results…

Genomics · Quantitative Biology 2012-08-20 Ryan M. Layer , Kevin Skadron , Gabriel Robins , Ira M. Hall , Aaron R. Quinlan
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