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Maximum likelihood estimation (MLE) is a statistical method used to estimate the parameters of a probability distribution that best explain the observed data. In the context of text generation, MLE is often used to train generative language…

Computation and Language · Computer Science 2023-10-27 Chenze Shao , Zhengrui Ma , Min Zhang , Yang Feng

This paper derives a unifying theorem establishing consistency results for a broad class of tree-based algorithms. It improves current results in two aspects. First of all, it can be applied to algorithms that vary from traditional Random…

Statistics Theory · Mathematics 2024-02-22 Ricardo Blum , Munir Hiabu , Enno Mammen , Joseph T. Meyer

Model ensembling is a well-established technique for improving the performance of machine learning models. Conventionally, this involves averaging the output distributions of multiple models and selecting the most probable label. This idea…

Machine Learning · Computer Science 2026-05-26 Jiale Fu , Yuchu Jiang , Peijun Wu , Chonghan Liu , Joey Tianyi Zhou , Xu Yang

Forward-time models of diversification (i.e., speciation and extinction) produce phylogenetic trees that grow "vertically" as time goes by. Pruning the extinct lineages out of such trees leads to natural models for reconstructed trees…

Populations and Evolution · Quantitative Biology 2013-08-07 Amaury Lambert , Tanja Stadler

Recently maximum pseudo-likelihood (MPL) inference method has been successfully applied to statistical physics models with intractable likelihoods. We use information theory to derive a relation between the pseudo-likelihood and likelihood…

Disordered Systems and Neural Networks · Physics 2015-06-18 Alexander Mozeika , Onur Dikmen , Joonas Piili

Recently, considerable effort has been put into developing fast algorithms to reconstruct a rooted phylogenetic network that explains two rooted phylogenetic trees and has a minimum number of hybridization vertices. With the standard…

Populations and Evolution · Quantitative Biology 2011-09-16 Celine Scornavacca , Simone Linz , Benjamin Albrecht

In 'no common mechanism' (NCM) models of character evolution, each character can evolve on a phylogenetic tree under a partially or totally separate process (e.g. with its own branch lengths). In such cases, the usual conditions that…

Populations and Evolution · Quantitative Biology 2009-12-02 Mike Steel

Ensemble trees are a popular machine learning model which often yields high prediction performance when analysing structured data. Although individual small decision trees are deemed explainable by nature, an ensemble of large trees is…

Logic in Computer Science · Computer Science 2021-03-04 Gelin Zhang , Zhe Hou , Yanhong Huang , Jianqi Shi , Hadrien Bride , Jin Song Dong , Yongsheng Gao

In this study, we investigate the problem of comparing gene trees reconciled with the same species tree using a novel semi-metric, called the Path-Label Reconciliation (PLR) dissimilarity measure. This approach not only quantifies…

Variable selection is an old and pervasive problem in regression analysis. One solution is to impose a lasso penalty to shrink parameter estimates toward zero and perform continuous model selection. The lasso-penalized mixture of linear…

Applications · Statistics 2016-05-04 Luke R. Lloyd-Jones , Hien D. Nguyen , Geoffrey J. McLachlan

Nonparametric maximum likelihood (NPML) for mixture models is a technique for estimating mixing distributions that has a long and rich history in statistics going back to the 1950s, and is closely related to empirical Bayes methods.…

Methodology · Statistics 2018-01-15 Long Feng , Lee H. Dicker

A metric phylogenetic tree relating a collection of taxa induces weighted rooted triples and weighted quartets for all subsets of three and four taxa, respectively. New intertaxon distances are defined that can be calculated from these…

Populations and Evolution · Quantitative Biology 2020-02-12 Samaneh Yourdkhani , John A. Rhodes

Auto-regressive sequence generative models trained by Maximum Likelihood Estimation suffer the exposure bias problem in practical finite sample scenarios. The crux is that the number of training samples for Maximum Likelihood Estimation is…

Machine Learning · Statistics 2020-07-14 Yuxuan Song , Ning Miao , Hao Zhou , Lantao Yu , Mingxuan Wang , Lei Li

We consider the problem of estimating species trees from unrooted gene tree topologies in the presence of incomplete lineage sorting, a common phenomenon that creates gene tree heterogeneity in multilocus datasets. One popular class of…

Populations and Evolution · Quantitative Biology 2018-12-21 Sebastien Roch

Probabilistic mixture models have been widely used for different machine learning and pattern recognition tasks such as clustering, dimensionality reduction, and classification. In this paper, we focus on trying to solve the most common…

Machine Learning · Computer Science 2020-04-08 Gustavo A Valencia-Zapata , Daniel Mejia , Gerhard Klimeck , Michael Zentner , Okan Ersoy

Most of major algorithms for phylogenetic tree reconstruction assume that sequences in the analyzed set either do not have any offspring, or that parent sequences can maximally mutate into just two descendants. The graph resulting from such…

Populations and Evolution · Quantitative Biology 2013-10-09 Piotr Plonski , Jan P. Radomski

The maximum parsimony phylogenetic tree reconstruction problem is NP-hard, presenting a computational bottleneck for classical computing and motivating the exploration of emerging paradigms like quantum computing. To this end, we design…

Quantum Physics · Physics 2026-04-20 Jiawei Zhang , Yibo Chen , Yang Zhou , Jun-Han Huang

Ensemble methods are among the state-of-the-art predictive modeling approaches. Applied to modern big data, these methods often require a large number of sub-learners, where the complexity of each learner typically grows with the size of…

Machine Learning · Computer Science 2018-10-29 Amichai Painsky , Saharon Rosset

The mutational heterogeneity of tumours can be described with a tree representing the evolutionary history of the tumour. With noisy sequencing data there may be uncertainty in the inferred tree structure, while we may also wish to study…

Computational Complexity · Computer Science 2025-01-14 Luís Cunha , Jack Kuipers , Thiago Lopes

Gene tree/species tree reconciliation is a recent decisive progress in phylo-genetic methods, accounting for the possible differences between gene histories and species histories. Reconciliation consists in explaining these differences by…

Quantitative Methods · Quantitative Biology 2017-10-05 Damir Hasic , Eric Tannier
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