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We propose a hierarchical architecture for efficiently computing high-quality solutions to structured mixed-integer programs (MIPs). To reduce computational effort, our approach decouples the original problem into a higher level problem and…

Optimization and Control · Mathematics 2025-12-04 Stefan Clarke , Bartolomeo Stellato

A common problem in phylogenetics is to try to infer a species phylogeny from gene trees. We consider different variants of this problem. The first variant, called Unrestricted Minimal Episodes Inference, aims at inferring a species tree…

Populations and Evolution · Quantitative Biology 2019-08-12 Leo van Iersel , Remie Janssen , Mark Jones , Yukihiro Murakami , Norbert Zeh

Nature-inspired metaheuristic algorithms are important components of artificial intelligence, and are increasingly used across disciplines to tackle various types of challenging optimization problems. This paper demonstrates the usefulness…

Neural and Evolutionary Computing · Computer Science 2024-08-20 Elvis Han Cui , Zizhao Zhang , Culsome Junwen Chen , Weng Kee Wong

Feature selection is a combinatorial optimization problem that is NP-hard. Conventional approaches often employ heuristic or greedy strategies, which are prone to premature convergence and may fail to capture subtle yet informative…

Machine Learning · Computer Science 2025-10-22 Yusi Fan , Tian Wang , Zhiying Yan , Chang Liu , Qiong Zhou , Qi Lu , Zhehao Guo , Ziqi Deng , Wenyu Zhu , Ruochi Zhang , Fengfeng Zhou

Evolutionary and bioinspired computation are crucial for efficiently addressing complex optimization problems across diverse application domains. By mimicking processes observed in nature, like evolution itself, these algorithms offer…

Neural and Evolutionary Computing · Computer Science 2025-01-14 Daniel Molina , Javier Del Ser , Javier Poyatos , Francisco Herrera

A good classification method should yield more accurate results than simple heuristics. But there are classification problems, especially high-dimensional ones like the ones based on image/video data, for which simple heuristics can work…

Machine Learning · Statistics 2018-06-15 Tarun Yellamraju , Jonas Hepp , Mireille Boutin

Neural Combinatorial Optimization approaches have recently leveraged the expressiveness and flexibility of deep neural networks to learn efficient heuristics for hard Combinatorial Optimization (CO) problems. However, most of the current…

Machine Learning · Computer Science 2022-10-04 Sahil Manchanda , Sofia Michel , Darko Drakulic , Jean-Marc Andreoli

Much combinatorial optimisation problems constitute a non-polynomial (NP) hard optimisation problem, i.e., they can not be solved in polynomial time. One such problem is finding the shortest route between two nodes on a graph.…

Machine Learning · Statistics 2017-09-08 Alessandro Bay , Biswa Sengupta

Inferring concerted changes among biological traits along an evolutionary history remains an important yet challenging problem. Besides adjusting for spurious correlation induced from the shared history, the task also requires sufficient…

The fundamental task of classification given a limited number of training data samples is considered for physical systems with known parametric statistical models. The standalone learning-based and statistical model-based classifiers face…

Machine Learning · Computer Science 2022-02-01 Alireza Nooraiepour , Waheed U. Bajwa , Narayan B. Mandayam

This paper surveys the trend of leveraging machine learning to solve mixed integer programming (MIP) problems. Theoretically, MIP is an NP-hard problem, and most of the combinatorial optimization (CO) problems can be formulated as the MIP.…

Artificial Intelligence · Computer Science 2022-03-08 Jiayi Zhang , Chang Liu , Junchi Yan , Xijun Li , Hui-Ling Zhen , Mingxuan Yuan

Background: Haplotypes, the ordered lists of single nucleotide variations that distinguish chromosomal sequences from their homologous pairs, may reveal an individual's susceptibility to hereditary and complex diseases and affect how our…

Social and Information Networks · Computer Science 2019-11-28 Abishek Sankararaman , Haris Vikalo , François Baccelli

The amount of completely sequenced chloroplast genomes increases rapidly every day, leading to the possibility to build large scale phylogenetic trees of plant species. Considering a subset of close plant species defined according to their…

Artificial Intelligence · Computer Science 2015-04-21 Bassam AlKindy , Christophe Guyeux , Jean-François Couchot , Michel Salomon , Christian Parisod , Jacques M. Bahi

Motivated by applications in neuroanatomy, we propose a novel methodology for estimating the heritability which corresponds to the proportion of phenotypic variance which can be explained by genetic factors. Estimating this quantity for…

Statistics Theory · Mathematics 2016-06-09 Anna Bonnet , Céline Lévy-Leduc , Elisabeth Gassiat , Roberto Toro , Thomas Bourgeron

Nowadays genetic algorithm (GA) is greatly used in engineering pedagogy as an adaptive technique to learn and solve complex problems and issues. It is a meta-heuristic approach that is used to solve hybrid computation challenges. GA…

Other Computer Science · Computer Science 2020-07-27 Tanweer Alam , Shamimul Qamar , Amit Dixit , Mohamed Benaida

One of the most critical issues in machine learning is the selection of appropriate hyper parameters for training models. Machine learning models may be able to reach the best training performance and may increase the ability to generalize…

Machine Learning · Computer Science 2023-02-23 Caner Erden , Halil Ibrahim Demir , Abdullah Hulusi Kökçam

The application of learning based methods to vehicle routing problems has emerged as a pivotal area of research in combinatorial optimization. These problems are characterized by vast solution spaces and intricate constraints, making…

Machine Learning · Computer Science 2025-03-14 Zhenwei Wang , Ruibin Bai , Tiehua Zhang

Complex engineering problems can be modelled as optimisation problems. For instance, optimising engines, materials, components, structure, aerodynamics, navigation, control, logistics, and planning is essential in aerospace. Metaheuristics…

Neural and Evolutionary Computing · Computer Science 2024-11-06 Carlos Alberto da Silva Junior , Marconi de Arruda Pereira , Angelo Passaro

Transportation is an essential area in the nowadays society, both for business sector and citizenry. There are different kinds of transportation systems, each one with its own characteristics. In the same way, various areas of knowledge can…

Artificial Intelligence · Computer Science 2020-03-26 Eneko Osaba

Nowadays hybrid evolutionary algorithms, i.e, heuristic search algorithms combining several mutation operators some of which are meant to implement stochastically a well known technique designed for the specific problem in question while…

Neural and Evolutionary Computing · Computer Science 2014-04-23 Boris Mitavskiy , Jun He