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Recent technological advances in cutting-edge ultrasensitive fluorescence microscopy have allowed single-molecule imaging experiments in living cells across all three domains of life to become commonplace. Single-molecule live-cell data is…

Biomolecules · Quantitative Biology 2015-04-15 Mark Leake

We study a quantum-enhanced differential measurement scheme that uses quantum probes and single-photon detectors to measure a minute defect in the absorption parameter of an analyte under investigation. For the purpose, we consider two…

Quantum Physics · Physics 2022-04-07 Byeong-Yoon Go , Changhyoup Lee , Kwang-Geol Lee

Two-dimensional electronic spectroscopy provides information on coupling and energy transfer between excited states on ultrafast timescales. Only recently, incoherent fluorescence detection has made it possible to combine this method with…

Optics · Physics 2025-05-14 Sanchayeeta Jana , Simon Durst , Lucas Ludwig , Markus Lippitz

Single-photon sources are a fundamental resource in quantum optics. The indistinguishability and purity of photons emitted from different sources are crucial (necessary, essential) properties for many quantum applications to ensure…

Quantum Physics · Physics 2020-07-15 Valérian Thiel , Alex O. C. Davis , Ke Sun , Peru D'Ornellas , Xian-Min Jin , Brian J. Smith

New methods are proposed to characterize the spectral-temporal distribution of single photons. The presented protocols take advantage of spectral filtering, frequency entanglement between two single photons the one of interest and a…

Quantum Physics · Physics 2022-06-29 Nicolas Fabre

As single-photon sources become more mature and are used more often in quantum information, communications and measurement applications, their characterization becomes more important. Single-photon-like light is often characterized by its…

We show a simple yet effective method that can be used to characterize the per pixel quantum efficiency and temporal resolution of a single photon event camera for quantum imaging applications. Utilizing photon pairs generated through…

Quantum Physics · Physics 2023-01-23 Victor Vidyapin , Yingwen Zhang , Duncan England , Benjamin Sussman

We experimentally investigate the fluorescence photon emission characteristics for single q-dots by using optical nanofibers. We demonstrate that single q-dots can be deposited along an optical nanofiber systematically and reproducibly with…

Mesoscale and Nanoscale Physics · Physics 2015-06-03 Ramachandrarao Yalla , K. P. Nayak , K. Hakuta

Single molecules in solid-state matrices have been proposed as sources of single-photon Fock states back 20 years ago. Their success in quantum optics and in many other research fields stems from the simple recipes used in the preparation…

A practical quantum measurement method based on the quantum nature of anti-bunching photon emission has been developed to detect single particles without the restriction of the diffraction limit. By simultane- ously counting the…

Quantum Physics · Physics 2013-05-24 Jin-Ming Cui , Fang-Wen Sun , Xiang-Dong Chen , Zhao-Jun Gong , Guang-Can Guo

The detection of fluorescence with submolecular resolution enables the exploration of spatially varying photon yields and vibronic properties at the single-molecule level. By placing individual polycyclic aromatic hydrocarbon molecules into…

Mesoscale and Nanoscale Physics · Physics 2018-08-01 Jörg Kröger , Benjamin Doppagne , Fabrice Scheurer , Guillaume Schull

Erasing quantum-mechanical distinguishability is of fundamental interest and also of practical importance, particularly in subject areas related to quantum information processing. We demonstrate a method applicable to optical systems in…

Quantum Physics · Physics 2015-06-05 Monika Patel , Joseph B. Altepeter , Yu-Ping Huang , Neal N. Oza , Prem Kumar

Single photons produced by fundamentally dissimilar physical processes will in general not be indistinguishable. We show how photons produced from a quantum dot and by parametric down-conversion in a nonlinear crystal can be manipulated to…

Recent theoretical studies in quantum spectroscopy have emphasized the potential of non-classical correlations in entangled photon pairs for selectively targeting specific nonlinear optical processes in nonlinear optical responses. However,…

Chemical Physics · Physics 2026-04-21 Yuta Fujihashi , Ozora Iso , Ryosuke Shimizu , Akihito Ishizaki

By using the zero-phonon line emission of an individual organic molecule, we realized a source of indistinguishable single photons in the near infrared. A Hong-Ou-Mandel interference experiment is performed and a two-photon coalescence…

Quantum Physics · Physics 2015-05-20 Jean-Baptiste Trebbia , Philippe Tamarat , Brahim Lounis

We have built a quantum light source capable of producing different types of quantum states. The quantum light source is based on entangled state preparation in the process of spontaneous parametric down-conversion. The single-photon…

There are many ways of calculating photon statistics in quantum optics in general and single molecule spectroscopy in particular such as the generating function method, the quantum jump approach or time ordering methods. In this paper…

Optics · Physics 2007-10-30 Faina Shikerman , Yong He , Eli Barkai

Recording the fluorescence of a magneto-optical trap (MOT) is a standard tool for measuring atom numbers in experiments with ultracold atoms. When trapping few atoms in a small MOT, the emitted fluorescence increases with the atom number in…

Quantum Gases · Physics 2021-03-17 Martin Schlederer , Alexandra Mozdzen , Thomas Lompe , Henning Moritz

Temporal-spectral modes of light provide a fundamental window into the nature of atomic and molecular systems and offer robust means for information encoding. Methods to precisely characterize the temporal-spectral state of light at the…

Quantum Physics · Physics 2018-08-29 Alex O. C. Davis , Valérian Thiel , Michał Karpiński , Brian J. Smith

Standard deviation measurements of intensity profiles of stationary single fluorescent molecules are useful for studying axial localization, molecular orientation, and a fluorescence imaging system's spatial resolution. Here we report on…

Quantitative Methods · Quantitative Biology 2015-05-13 Michael C. DeSantis , Shawn H. DeCenzo , Je-Luen Li , Y. M. Wang