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Parameters in mathematical models for glioblastoma multiforme (GBM) tumour growth are highly patient specific. Here we aim to estimate parameters in a Cahn-Hilliard type diffuse interface model in an optimised way using model order…

Numerical Analysis · Mathematics 2023-07-19 Abramo Agosti , Pasquale Ciarletta , Harald Garcke , Michael Hinze

The modern workflow for radiation therapy treatment planning involves mathematical optimization to determine optimal treatment machine parameters for each patient case. The optimization problems can be computationally expensive, requiring…

Mathematical Software · Computer Science 2023-05-30 Felix Liu , Måns I. Andersson , Albin Fredriksson , Stefano Markidis

First-order methods such as stochastic gradient descent (SGD) are currently the standard algorithm for training deep neural networks. Second-order methods, despite their better convergence rate, are rarely used in practice due to the…

Machine Learning · Computer Science 2019-09-26 Tianle Cai , Ruiqi Gao , Jikai Hou , Siyu Chen , Dong Wang , Di He , Zhihua Zhang , Liwei Wang

Large-scale text-to-image diffusion models, while powerful, suffer from prohibitive computational cost. Existing one-shot network pruning methods can hardly be directly applied to them due to the iterative denoising nature of diffusion…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Junhan Zhu , Hesong Wang , Mingluo Su , Zefang Wang , Huan Wang

The problem Power Dominating Set (PDS) is motivated by the placement of phasor measurement units to monitor electrical networks. It asks for a minimum set of vertices in a graph that observes all remaining vertices by exhaustively applying…

Data Structures and Algorithms · Computer Science 2023-06-19 Thomas Bläsius , Max Göttlicher

We propose a redshift estimator for the long ($T_{90} > 20$) gamma-ray bursts (GRBs) observed by the BATSE. It is based on an empirical relation between the redshift and the power-law index of power density spectra (PDSs) of the observed…

Astrophysics · Physics 2007-05-23 Heon-Young Chang , Suk-Jin Yoon , Chul-Sung Choi

Recently, the Diffusion Probabilistic Model (DPM)-based methods have achieved substantial success in the field of medical image segmentation. However, most of these methods fail to enable the diffusion model to learn edge features and…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Tingwei Liu , Miao Zhang , Leiye Liu , Jialong Zhong , Shuyao Wang , Yongri Piao , Huchuan Lu

We establish a high-resolution, high-performance, and high-confidence compressible multiphysics system in a Cartesian grid with irregular boundary topologies to simulate intensive blast waves propagating in large-scale and extremely complex…

Computational Physics · Physics 2024-11-06 Minsheng Huang , Pan Wang , Chengbao Yao , Lidong Cheng , Wenjun Ying

We propose to develop deep learning models that can predict Pareto optimal dose distributions by using any given set of beam angles, along with patient anatomy, as input to train the deep neural networks. We implement and compare two deep…

Medical Physics · Physics 2021-01-27 Gyanendra Bohara , Azar Sadeghnejad Barkousaraie , Steve Jiang , Dan Nguyen

Purpose: To determine whether alternative HDR prostate brachytherapy catheter patterns can result in improved dose distributions while providing better access and reducing trauma. Methods: Prostate HDR brachytherapy uses a grid of parallel…

Medical Physics · Physics 2015-05-13 J. Adam M. Cunha , I-Chow Hsu , Jean Pouliot

Purpose: Ultra-fast scintillation imaging has been shown to provide a unique tool for spatio-temporal dosimetry of conventional cyclotron and synchrocyclotron pencil beam scanning (PBS) deliveries, indicating the potential use for…

Radiotherapy (RT) is a critical cancer treatment, with volumetric modulated arc therapy (VMAT) being a commonly used technique that enhances dose conformity by dynamically adjusting multileaf collimator (MLC) positions and monitor units…

Medical Physics · Physics 2025-06-26 Stefanos Achlatis , Efstratios Gavves , Jan-Jakob Sonke

Generalized parton distributions (GPDs) have been investigated in the deeply virtual Compton scattering (DVCS) to solve the proton spin puzzle. On the other hand, the generalized distribution amplitudes (GDAs) can be studied in the…

High Energy Physics - Phenomenology · Physics 2018-08-21 Qin-Tao Song

In carbon-ion radiotherapy, single-beam delivery each day in alternate directions has been commonly practiced for operational efficiency, taking advantage of the Bragg peak and the relative biological effectiveness (RBE) for uniform dose…

Medical Physics · Physics 2018-01-24 Nobuyuki Kanematsu , Taku Inaniwa

Automated grading of diabetic retinopathy (DR) faces several critical challenges: subtle inter-grade visual distinctions in fine-grained lesion patterns, distributional discrepancies induced by heterogeneous imaging devices and acquisition…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Yiqun Wang

Radiotherapy treatment planning currently requires many trail-and-error iterations between the planner and treatment planning system, as well as between the planner and physician for discussion/consultation. The physician's preferences for…

Medical Physics · Physics 2019-08-01 Dan Nguyen , Azar Sadeghnejad Barkousaraie , Chenyang Shen , Xun Jia , Steve Jiang

When treating moving tumors, the precise delivery of proton therapy by pencil beam scanning (PBS) is challenged by the interplay effect. Although several 4D-optimization methods have been proposed, what is the most beneficial motion…

Medical Physics · Physics 2025-01-29 Ivar Bengtsson , Anders Forsgren , Albin Fredriksson

Stereotactic body radiotherapy (SBRT) is characterized by delivering a high amount of dose in a short period of time. In SBRT the dose is delivered using open fields (e.g., beam's-eye-view) known as "apertures". Mathematical methods can be…

Medical Physics · Physics 2015-06-15 Hamed Yarmand , David Craft

We study diffusion and consensus based optimization of a sum of unknown convex objective functions over distributed networks. The only access to these functions is through stochastic gradient oracles, each of which is only available at a…

Numerical Analysis · Computer Science 2015-09-01 N. Denizcan Vanli , Muhammed O. Sayin , Suleyman S. Kozat

Power losses in electrical power systems especially, distribution systems, occur due to several environmental and technical factors. Transmission & Distribution line losses are normally 17% and 50% respectively. These losses are due to the…

Systems and Control · Electrical Eng. & Systems 2023-07-13 Umar Jamil