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Laser-accelerated protons have a great potential for innovative experiments in radiation biology due to the sub-picosecond pulse duration and high dose rate achievable. However, the broad angular divergence makes them not optimal for…

Medical Physics · Physics 2019-11-13 Marco Cavallone , Alessandro Flacco , Victor Malka

The increasing distributed and renewable energy resources and controllable devices in distribution systems make fast distribution system state estimation (DSSE) crucial in system monitoring and control. We consider a large multi-phase…

Optimization and Control · Mathematics 2020-05-22 Xinyang Zhou , Zhiyuan Liu , Yi Guo , Changhong Zhao , Jianqiao Huang , Lijun Chen

Treatment planning, which is a critical component of the radiotherapy workflow, is typically carried out by a medical physicist in a time-consuming trial-and-error manner. Previous studies have proposed knowledge-based or…

Image and Video Processing · Electrical Eng. & Systems 2024-03-29 Yiwen Zhang , Chuanpu Li , Liming Zhong , Zeli Chen , Wei Yang , Xuetao Wang

We present new methods for radiative transfer on hierarchial grids. We develop a new method for calculating the scattered flux that employs the grid structure to speed up the computation. We describe a novel subiteration algorithm that can…

Instrumentation and Methods for Astrophysics · Physics 2015-06-05 T. Lunttila , M. Juvela

Diagnosis of breast cancer has been well studied in the past. Multiple linear programming models have been devised to approximate the relationship between cell features and tumour malignancy. However, these models are less capable in…

Machine Learning · Computer Science 2020-02-21 Ke Quan

In this work, we propose a Machine Learning model that generates an adjustable 3D dose distribution for external beam radiation therapy for head-and-neck cancer treatments. In contrast to existing Machine Learning methods that provide a…

An essential component in proton radiotherapy is the algorithm to calculate the radiation dose to be delivered to the patient. The most common dose algorithms are fast but they are approximate analytical approaches. However their level of…

Medical Physics · Physics 2015-05-20 Pablo P Yepes , Dragan Mirkovic , Phillip J Taddei

Due to the large combinatorial problem, current beam orientation optimization algorithms for radiotherapy, such as column generation (CG), are typically heuristic or greedy in nature, leading to suboptimal solutions. We propose a…

Medical Physics · Physics 2020-04-15 Azar Sadeghnejad-Barkousaraie , Gyanendra Bohara , Steve Jiang , Dan Nguyen

We present and implement the concept of the Fourier-domain dedispersion (FDD) algorithm, a brute-force incoherent dedispersion algorithm. This algorithm corrects the frequency-dependent dispersion delays in the arrival time of radio…

Instrumentation and Methods for Astrophysics · Physics 2022-01-05 C. G. Bassa , J. W. Romein , B. Veenboer , S. van der Vlugt , S. J. Wijnholds

Purpose: The FLASH effect, which reduces the radiosensitivity of healthy tissue while maintaining tumor control at high dose rates, has shown potential for improving radiation therapy. Conformal FLASH proton therapy involves advanced…

Medical Physics · Physics 2023-04-13 Sylvain Deffet , Edmond Sterpin

In radiotherapy, a trade-off exists between computational workload/speed and dose calculation accuracy. Calculation methods like pencil-beam convolution can be much faster than Monte-Carlo methods, but less accurate. The dose difference,…

Medical Physics · Physics 2020-05-18 Yixun Xing , Ph. D. , You Zhang , Ph. D. , Dan Nguyen , Ph. D. , Mu-Han Lin , Ph. D. , Weiguo Lu , Ph. D. , Steve Jiang , Ph. D

Deep neural networks (DNNs) have been proven to be effective in solving many real-life problems, but its high computation cost prohibits those models from being deployed to edge devices. Pruning, as a method to introduce zeros to model…

Machine Learning · Computer Science 2021-12-22 Fei Sun , Minghai Qin , Tianyun Zhang , Xiaolong Ma , Haoran Li , Junwen Luo , Zihao Zhao , Yen-Kuang Chen , Yuan Xie

We present a detailed study on application of factor graphs and the belief propagation (BP) algorithm to the power system state estimation (SE) problem. We start from the BP solution for the linear DC model, for which we provide a detailed…

Information Theory · Computer Science 2018-11-21 Mirsad Cosovic

Radiation therapy is the primary method used to treat cancer in the clinic. Its goal is to deliver a precise dose to the planning target volume (PTV) while protecting the surrounding organs at risk (OARs). However, the traditional workflow…

Image and Video Processing · Electrical Eng. & Systems 2024-04-10 Tara Gheshlaghi , Shahabedin Nabavi , Samire Shirzadikia , Mohsen Ebrahimi Moghaddam , Nima Rostampour

Timing analysis is a powerful tool with which to shed light on the still obscure emission physics and geometry of the prompt emission of GRBs. Fourier power density spectra (PDS) characterise time series as stochastic processes and can be…

High Energy Astrophysical Phenomena · Physics 2016-04-20 C. Guidorzi , S. Dichiara , L. Amati

Purpose: To provide a fast computational method, based on the proximal graph solver (POGS) - a convex optimization solver using the alternating direction method of multipliers (ADMM), for calculating an optimal treatment plan in rotating…

Medical Physics · Physics 2018-02-07 Myung Cho , Xiaodong Wu , Hossein Dakhah , Jirong Yi , Ryan T. Flynn , Yusung Kim , Weiyu Xu

Purpose: To develop a machine learning-based, 3D dose prediction methodology for Gamma Knife (GK) radiosurgery. The methodology accounts for cases involving targets of any number, size, and shape. Methods: Data from 322 GK treatment plans…

Medical Physics · Physics 2023-01-09 Binghao Zhang , Aaron Babier , Timothy C. Y. Chan , Mark Ruschin

Single minibeams of protons, $^{4}$He, $^{12}$C and $^{16}$O in water were modeled with Geant4, and their dose distributions were parameterized with double-Gauss-Rutherford (DGR) functions. Dose distributions from arrays of 16 parallel…

Medical Physics · Physics 2024-12-30 Savva Savenkov , Alexandr Svetlichnyi , Igor Pshenichnov

The Gradient Boosted Tree (GBT) algorithm is one of the most popular machine learning algorithms used in production, for tasks that include Click-Through Rate (CTR) prediction and learning-to-rank. To deal with the massive datasets…

Machine Learning · Computer Science 2019-05-30 Theodore Vasiloudis , Hyunsu Cho , Henrik Boström

The stochastic gradient descent (SGD) algorithm is the algorithm we use to train neural networks. However, it remains poorly understood how the SGD navigates the highly nonlinear and degenerate loss landscape of a neural network. In this…

Machine Learning · Computer Science 2025-06-13 Liu Ziyin , Hongchao Li , Masahito Ueda