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We systematically study the computational complexity of a broad class of computational problems in phylogenetic reconstruction. The class contains for example the rooted triple consistency problem, forbidden subtree problems, the quartet…

Computational Complexity · Computer Science 2017-08-15 Manuel Bodirsky , Peter Jonsson , Trung Van Pham

Phylogenetic trees are widely used to display estimates of how groups of species evolved. Each phylogenetic tree can be seen as a collection of clusters, subgroups of the species that evolved from a common ancestor. When phylogenetic trees…

Populations and Evolution · Quantitative Biology 2009-10-19 Leo van Iersel , Steven Kelk , Regula Rupp , Daniel Huson

A classical problem in phylogenetic tree analysis is to decide whether there is a phylogenetic tree $T$ that contains all information of a given collection $\cP$ of phylogenetic trees. If the answer is "yes" we say that $\cP$ is compatible…

Combinatorics · Mathematics 2010-06-29 Stefan Grünewald

Phylogenetic networks are important for the study of evolution. The number of methods to find such networks is increasing, but most such methods can only reconstruct small networks. To find bigger networks, one can attempt to combine small…

Discrete Mathematics · Computer Science 2019-12-10 Remie Janssen , Mark Jones , Yukihiro Murakami

Rooted acyclic graphs appear naturally when the phylogenetic relationship of a set $X$ of taxa involves not only speciations but also recombination, horizontal transfer, or hybridization, that cannot be captured by trees. A variety of…

Populations and Evolution · Quantitative Biology 2022-04-29 Marc Hellmuth , David Schaller , Peter F. Stadler

Background: Tree reconciliation problems have long been studied in phylogenetics. A particular variant of the reconciliation problem for a gene tree T and a species tree S assumes that for each interior vertex x of T it is known whether x…

Discrete Mathematics · Computer Science 2017-05-12 Maribel Hernandez-Rosales , Marc Hellmuth , Nicolas Wieseke , Katharina T. Huber , Vincent Moulton , Peter F. Stadler

Rooted phylogenetic networks provide a more complete representation of the ancestral relationship between species than phylogenetic trees when reticulate evolutionary processes are at play. One way to reconstruct a phylogenetic network is…

Combinatorics · Mathematics 2020-12-02 Allan Bai , Peter Erdos , Charles Semple , Mike Steel

In the NP-hard Optimizing PD with Dependencies (PDD) problem, the input consists of a phylogenetic tree $T$ over a set of taxa $X$, a food-web that describes the prey-predator relationships in $X$, and integers $k$ and $D$. The task is to…

Computational Complexity · Computer Science 2024-05-28 Christian Komusiewicz , Jannik Schestag

Rooted phylogenetic networks allow biologists to represent evolutionary relationships between present-day species by revealing ancestral speciation and hybridization events. A convenient and well-studied class of such networks are…

Populations and Evolution · Quantitative Biology 2026-02-02 Qiang Zhang , Mike Steel

Phylogenetic trees represent certain species and their likely ancestors. In such a tree, present-day species are leaves and an edge from u to v indicates that u is an ancestor of v. Weights on these edges indicate the phylogenetic distance.…

Populations and Evolution · Quantitative Biology 2025-10-08 Jannik Schestag

Reconstructing the evolutionary past of a family of genes is an important aspect of many genomic studies. To help with this, simple operations on a set of sequences called orthology relations may be employed. In addition to being…

Discrete Mathematics · Computer Science 2016-03-16 K. T. Huber , G. E. Scholz

Phylogenetic networks are graphs that are used to represent evolutionary relationships between different taxa. They generalize phylogenetic trees since for example, unlike trees, they permit lineages to combine. Recently, there has been…

Populations and Evolution · Quantitative Biology 2025-08-05 Katharina T. Huber , Leo van Iersel , Mark Jones , Vincent Moulton , Leonie Veenema - Nipius

Phylogenetic networks are becoming of increasing interest to evolutionary biologists due to their ability to capture complex non-treelike evolutionary processes. From a combinatorial point of view, such networks are certain types of rooted…

Combinatorics · Mathematics 2019-10-21 Katharina T. Huber , Guillaume E. Scholz

We consider the classic problem of Network Reliability. A network is given together with a source vertex, one or more target vertices, and probabilities assigned to each of the edges. Each edge appears in the network with its associated…

Combinatorics · Mathematics 2019-03-20 Amir Kafshdar Goharshady , Fatemeh Mohammadi

Orthologous genes, which arise through speciation, play a key role in comparative genomics and functional inference. In particular, graph-based methods allow for the inference of orthology estimates without prior knowledge of the underlying…

Populations and Evolution · Quantitative Biology 2025-02-14 Anna Lindeberg , Guillaume E. Scholz , Nicolas Wieseke , Marc Hellmuth

The structure of an evolving network contains information about its past. Extracting this information efficiently, however, is, in general, a difficult challenge. We formulate a fast and efficient method to estimate the most likely history…

Physics and Society · Physics 2020-09-16 Gábor Timár , Rui A. da Costa , Sergey N. Dorogovtsev , José F. F. Mendes

Phylogenetic trees are simple models of evolutionary processes. They describe conditionally independent divergent evolution of taxa from common ancestors. Phylogenetic trees commonly do not have enough flexibility to adequately model all…

Populations and Evolution · Quantitative Biology 2025-11-11 Jonathan D. Mitchell , Barbara R. Holland

It is required to find an optimal order of constructing the edges of a network so as to minimize the sum of the weighted connection times of relevant pairs of vertices. Construction can be performed anytime anywhere in the network, with a…

Data Structures and Algorithms · Computer Science 2021-04-20 Igor Averbakh

Rooted phylogenetic networks are often constructed by combining trees, clusters, triplets or characters into a single network that in some well-defined sense simultaneously represents them all. We review these four models and investigate…

Populations and Evolution · Quantitative Biology 2010-04-30 Leo van Iersel , Steven Kelk

Deciding whether a graph can be embedded in a grid using only unit-length edges is NP-complete, even when restricted to binary trees. However, it is not difficult to devise a number of graph classes for which the problem is polynomial, even…

Data Structures and Algorithms · Computer Science 2012-04-13 Vinícius G. P. de Sá , Guilherme D. da Fonseca , Raphael Machado , Celina M. H. de Figueiredo
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