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In this paper, we study the large-scale protein interaction network of yeast uti lizing a stochastic method based upon percolation of random graphs. In order to find the global features of connectivities in the network, we introduce numeric…

Statistical Mechanics · Physics 2007-05-23 Chen-Shan Chin , Manoj Pratim Samanta

Link prediction is one of the fundamental problems in network analysis. In many applications, notably in genetics, a partially observed network may not contain any negative examples of absent edges, which creates a difficulty for many…

Machine Learning · Statistics 2013-01-30 Yunpeng Zhao , Elizaveta Levina , Ji Zhu

Stochastic reaction network models are widely utilized in biology and chemistry to describe the probabilistic dynamics of biochemical systems in general, and gene interaction networks in particular. Most often, statistical analysis and…

Quantitative Methods · Quantitative Biology 2017-10-18 Eugenio Cinquemani

Understanding the mathematical properties of graphs underling biological systems could give hints on the evolutionary mechanisms behind these structures. In this article we perform a complete statistical analysis over thousands of graphs…

Molecular Networks · Quantitative Biology 2019-08-29 D. Gamermann , J. Triana , R. Jaime

We consider an evolving network of a fixed number of nodes. The allocation of edges is a dynamical stochastic process inspired by biological reproduction dynamics, namely by deleting and duplicating existing nodes and their edges. The…

Statistical Mechanics · Physics 2007-09-14 Henrik Jeldtot Jensen

We consider a non-conserving zero-range process with hopping rate proportional to the number of particles at each site. Particles are added to the system with a site-dependent creation rate, and removed from the system with a uniform…

Statistical Mechanics · Physics 2019-09-04 Pascal Grange

We consider a neural network with adapting synapses whose dynamics can be analitically computed. The model is made of $N$ neurons and each of them is connected to $K$ input neurons chosen at random in the network. The synapses are…

Disordered Systems and Neural Networks · Physics 2009-10-30 G. Lattanzi , G. Nardulli , G. Pasquariello , S. Stramaglia

Geometric constraints impact the formation of a broad range of spatial networks, from amino acid chains folding to proteins structures to rearranging particle aggregates. How the network of interactions dynamically self-organizes in such…

Molecular Networks · Quantitative Biology 2016-10-19 Nora Molkenthin , Marc Timme

Widely used closed product-form networks have emerged recently as a primary model of stochastic growth of sub-cellular structures, e.g., cellular filaments. In the baseline model, homogeneous monomers attach and detach stochastically to…

Probability · Mathematics 2020-07-30 Predrag Jelenkovic , Jane Kondev , Lishibanya Mohapatra , Petar Momcilovic

We present a simple model of network growth and solve it by writing down the dynamic equations for its macroscopic characteristics like the degree distribution and degree correlations. This allows us to study carefully the percolation…

Statistical Mechanics · Physics 2014-04-28 Hans Hooyberghs , Bert Van Schaeybroeck , Joseph O. Indekeu

We study the asymptotic behavior of multiscale stochastic gene networks using weak limits of Markov jump processes. Depending on the time and concentration scales of the system we distinguish four types of limits: continuous piecewise…

Probability · Mathematics 2011-01-10 Alina Crudu , Arnaud Debussche , Aurélie Muller , Ovidiu Radulescu

In several real-world networks like the Internet, WWW etc., the number of links grow in time in a non-linear fashion. We consider growing networks in which the number of outgoing links is a non-linear function of time but new links between…

Statistical Mechanics · Physics 2009-11-10 Parongama Sen

Many biological networks have been labelled scale-free as their degree distribution can be approximately described by a powerlaw distribution. While the degree distribution does not summarize all aspects of a network it has often been…

Molecular Networks · Quantitative Biology 2007-05-23 M. P. H. Stumpf , P. J. Ingram , I. Nouvel , C. Wiuf

Networks in nature are often formed within a spatial domain in a dynamical manner, gaining links and nodes as they develop over time. We propose a class of spatially-based growing network models and investigate the relationship between the…

Physics and Society · Physics 2013-12-30 Ari Zitin , Alex Gorowora , Shane Squires , Mark Herrera , Thomas M. Antonsen , Michelle Girvan , Edward Ott

We consider a new class of non Markovian processes with a countable number of interacting components. At each time unit, each component can take two values, indicating if it has a spike or not at this precise moment. The system evolves as…

Probability · Mathematics 2015-06-12 Antonio Galves , Eva Löcherbach

There have been many studies to examine whether one trait is correlated with another trait across a group of present-day species (for example, do species with larger brains tend to have longer gestation times. Since the introduction of the…

Populations and Evolution · Quantitative Biology 2023-09-07 Albert Ch. Soewongsono , Barbara R. Holland , Malgorzata M. O'Reilly

Probabilistic biological network growth models have been utilized for many tasks including but not limited to capturing mechanism and dynamics of biological growth activities, null model representation, capturing anomalies, etc. Well-known…

Molecular Networks · Quantitative Biology 2024-01-02 Emre Sefer

We present analytical results for the emerging structure of networks that evolve via a combination of growth (by node addition and random attachment) and contraction (by random node deletion). To this end we consider a network model in…

Statistical Mechanics · Physics 2022-10-25 Barak Budnick , Ofer Biham , Eytan Katzav

In a recent paper, Krapivsky and Redner (Phys. Rev. E, 71 (2005) 036118) proposed a new growing network model with new nodes being attached to a randomly selected node, as well to all ancestors of the target node. The model leads to a…

Physics and Society · Physics 2007-05-23 Sergi Valverde , Ricard V. Sole

In this paper we present the first mathematical analysis of the protein interaction network found in the yeast, S. cerevisiae. We show that, (a) the identified protein network display a characteristic scale-free topology that demonstrate…

Statistical Mechanics · Physics 2009-11-07 Hawoong Jeong , Sean P. Mason , Albert-Laszlo Barabasi , Zoltan N. Oltvai