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Epistatic interactions between mutations add substantial complexity to adaptive landscapes, and are often thought of as detrimental to our ability to predict evolution. Yet, patterns of global epistasis, in which the fitness effect of a…

Populations and Evolution · Quantitative Biology 2022-10-10 Juan Diaz-Colunga , Abigail Skwara , Karna Gowda , Ramon Diaz-Uriarte , Mikhail Tikhonov , Djordje Bajic , Alvaro Sanchez

Planning is a powerful approach to reinforcement learning with several desirable properties. However, it requires a model of the world, which is not readily available in many real-life problems. In this paper, we propose to learn a world…

Machine Learning · Computer Science 2020-11-24 Thor V. A. N. Olesen , Dennis T. T. Nguyen , Rasmus Berg Palm , Sebastian Risi

We consider the evolutionary trajectories traced out by an infinite population undergoing mutation-selection dynamics in static, uncorrelated random fitness landscapes. Starting from the population that consists of a single genotype, the…

Populations and Evolution · Quantitative Biology 2009-11-11 Kavita Jain , Joachim Krug

We study biological evolution in a high-dimensional genotype space in the regime of rare mutations and strong selection. The population performs an uphill walk which terminates at local fitness maxima. Assigning fitness randomly to…

Populations and Evolution · Quantitative Biology 2015-05-28 Johannes Neidhart , Joachim Krug

In epistatic fitness landscapes, the fitness effect of a mutation depends on the genetic background and may even switch between deleterious and beneficial depending on the presence of another mutation. Epistatic interactions may cause both…

Learning controllers that reproduce legged locomotion in nature has been a long-time goal in robotics and computer graphics. While yielding promising results, recent approaches are not yet flexible enough to be applicable to legged systems…

Robotics · Computer Science 2022-07-26 Daniel Ordonez-Apraez , Antonio Agudo , Francesc Moreno-Noguer , Mario Martin

The concept of a fitness landscape is a powerful metaphor that offers insight into various aspects of evolutionary processes and guidance for the study of evolution. Until recently, empirical evidence on the ruggedness of these landscapes…

Populations and Evolution · Quantitative Biology 2013-01-18 Ivan G. Szendro , Martijn F. Schenk , Jasper Franke , Joachim Krug , J. Arjan G. M. de Visser

Using Large Language Models (LLMs) in an evolutionary or other iterative search framework have demonstrated significant potential in automated algorithm design. However, the underlying fitness landscape, which is critical for understanding…

Artificial Intelligence · Computer Science 2025-08-28 Fei Liu , Qingfu Zhang , Jialong Shi , Xialiang Tong , Kun Mao , Mingxuan Yuan

We present a comparative study of methods for generating realistic, constrained small- to medium-scale road networks with built-in redundancy. In this research, we evaluate the proposed Evolutionary Algorithm (EA) with connectivity and…

Neural and Evolutionary Computing · Computer Science 2026-03-24 Artur Morys-Magiera , Marek Długosz , Paweł Skruch

Evolutionary algorithms have long been used for optimization problems where the appropriate size of solutions is unclear a priori. The applicability of this methodology is here investigated on the problem of designing a nano-particle (NP)…

Neural and Evolutionary Computing · Computer Science 2020-11-11 Michail-Antisthenis Tsompanas , Larry Bull , Andrew Adamatzky , Igor Balaz

In this work, we propose a novel approach for reinforcement learning driven by evolutionary computation. Our algorithm, dubbed as Evolutionary-Driven Reinforcement Learning (evo-RL), embeds the reinforcement learning algorithm in an…

Although Reinforcement Learning (RL) has shown to be capable of producing impressive results, its use is limited by the impact of its hyperparameters on performance. This often makes it difficult to achieve good results in practice.…

Machine Learning · Computer Science 2024-05-16 Aditya Mohan , Carolin Benjamins , Konrad Wienecke , Alexander Dockhorn , Marius Lindauer

We use fitness graphs, or directed cube graphs, for analyzing evolutionary reversibility. The main application is antimicrobial drug resistance. Reversible drug resistance has been observed both clinically and experimentally. If drug…

Populations and Evolution · Quantitative Biology 2023-07-28 Kristina Crona

On rugged fitness landscapes where sign epistasis is common, adaptation can often involve either individually beneficial "uphill" mutations or more complex mutational trajectories involving fitness valleys or plateaus. The dynamics of the…

Populations and Evolution · Quantitative Biology 2015-10-06 Ian E. Ochs , Michael M. Desai

This paper addresses the challenge of terrain-adaptive dynamic locomotion in humanoid robots, a problem traditionally tackled by optimization-based methods or reinforcement learning (RL). Optimization-based methods, such as model-predictive…

Robotics · Computer Science 2024-07-30 Shangqun Yu , Nisal Perera , Daniel Marew , Donghyun Kim

Humanoid robots have demonstrated robust locomotion capabilities using Reinforcement Learning (RL)-based approaches. Further, to obtain human-like behaviors, existing methods integrate human motion-tracking or motion prior in the RL…

Robotics · Computer Science 2025-06-13 Dewei Wang , Xinmiao Wang , Xinzhe Liu , Jiyuan Shi , Yingnan Zhao , Chenjia Bai , Xuelong Li

We consider evolution of a large population, where fitness of each organism is defined by many phenotypical traits. These traits result from expression of many genes. We propose a new model of gene regulation, where gene expression is…

Populations and Evolution · Quantitative Biology 2016-09-29 John Reinitz , Sergey Vakulenko , Dmitri Grigoriev , Andreas Weber

While the animals' Fin-to-Limb evolution has been well-researched in biology, such morphological transformation remains under-adopted in the modern design of advanced robotic limbs. This paper investigates a novel class of overconstrained…

Large language models (LLMs) are increasingly used to evolve programs and multi-agent systems, yet most existing approaches rely on overwrite-based mutations that maintain only a single candidate at a time. Such methods discard useful…

Artificial Intelligence · Computer Science 2025-12-18 Kamer Ali Yuksel

In evolution theory the concept of a fitness landscape has played an important role, evolution itself being portrayed as a hill-climbing process on a rugged landscape. In this article it is shown that in general, in the presence of other…

Adaptation and Self-Organizing Systems · Physics 2016-11-17 C. R. Stephens