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Is evolution always gradual or can it make leaps? We examine a mathematical model of an evolutionary process on a fitness landscape and obtain analytic solutions for the probability of multi-mutation leaps, that is, several mutations…

Populations and Evolution · Quantitative Biology 2022-10-12 Mikhail I. Katsnelson , Yuri I. Wolf , Eugene V. Koonin

When biological populations expand into new territory, the evolutionary outcomes can be strongly influenced by genetic drift, the random fluctuations in allele frequencies. Meanwhile, spatial variability in the environment can also…

Populations and Evolution · Quantitative Biology 2024-06-27 Jimmy Gonzalez Nuñez , Jayson Paulose , Wolfram Möbius , Daniel A. Beller

Understanding whether a population will survive and flourish or become extinct is a central question in population biology. One way of exploring this question is to study population dynamics using reaction-diffusion equations, where…

Populations and Evolution · Quantitative Biology 2022-01-10 Yifei Li , Pascal R. Buenzli , Matthew J. Simpson

We study a mathematical model describing the growth process of a population structured by age and a phenotypical trait, subject to aging, competition between individuals and rare mutations. Our goals are to describe the asymptotic behaviour…

Analysis of PDEs · Mathematics 2020-04-17 Samuel Nordmann , Benoît Perthame , Cécile Taing

We show how concepts from statistical physics, such as order parameter, thermodynamic limit, and quantum phase transition, translate into biological concepts in mutation-selection models for sequence evolution and can be used there. The…

Statistical Mechanics · Physics 2007-05-23 Joachim Hermisson , Oliver Redner , Holger Wagner , Ellen Baake

We consider a linear size-structured population model with diffusion in the size-space. Individuals are recruited into the population at arbitrary sizes. The model is equipped with generalized Wentzell-Robin (or dynamic) boundary…

Analysis of PDEs · Mathematics 2019-03-25 J. Z. Farkas , P. Hinow

We study the evolutionary dynamics of a maladapted population of self-replicating sequences on strongly correlated fitness landscapes. Each sequence is assumed to be composed of blocks of equal length and its fitness is given by a linear…

Populations and Evolution · Quantitative Biology 2015-05-18 Sarada Seetharaman , Kavita Jain

We consider an approximating sequence of interacting population models with branching, mutation and competition. Each individual is characterized by its trait and the traits of its ancestors. Birth- and death-events happen at exponential…

Probability · Mathematics 2014-12-08 Sandra Kliem

We review and extend results for mutation, selection, genetic drift, and migration in a one-dimensional continuous population. The population is described by a continuous limit of the stepping stone model, which leads to the stochastic…

Populations and Evolution · Quantitative Biology 2011-04-14 K. S. Korolev , Mikkel Avlund , Oskar Hallatschek , David R. Nelson

The coevolutionary dynamics in finite populations currently is investigated in a wide range of disciplines, as chemical catalysis, biological evolution, social and economic systems. The dynamics of those systems can be formulated within the…

Populations and Evolution · Quantitative Biology 2012-06-12 Jens Christian Claussen

The dynamics of two competing species in a finite size community is one of the most studied problems in population genetics and community ecology. Stochastic fluctuations lead, inevitably, to the extinction of one of the species, but the…

Populations and Evolution · Quantitative Biology 2016-11-30 Matan Danino , David A. Kessler , Nadav M. Shnerb

Both evolution and ecology have long been concerned with the impact of variable environmental conditions on observed levels of genetic diversity within and between species. We model the evolution of a quantitative trait under selection that…

Populations and Evolution · Quantitative Biology 2014-11-17 Hannes Svardal , Claus Rueffler , Joachim Hermisson

Convergence of discrete-time Markov chains with two timescales is a powerful tool to study stochastic evolutionary games in subdivided populations. Focusing on linear games within demes, convergence to a diffusion process for the strategy…

Populations and Evolution · Quantitative Biology 2024-11-05 Sabin Lessard

Existing theories for the evolution of aging and death treat senescence as a side-effect of strong selection for fertility. These theories are well-developed mathematically, but fit poorly with emerging experimental data. The data suggest…

Populations and Evolution · Quantitative Biology 2007-05-23 Josh Mitteldorf

The behavior of interacting populations typically displays irregular temporal and spatial patterns that are difficult to reconcile with an underlying deterministic dynamics. A classical example is the heterogeneous distribution of plankton…

Populations and Evolution · Quantitative Biology 2009-11-13 M. H. Vainstein , J. M. Rubi , J. M. G. Vilar

The n-person Prisoner's Dilemma is a widely used model for populations where individuals interact in groups. The evolutionary stability of populations has been analysed in the literature for the case where mutations in the population may be…

Populations and Evolution · Quantitative Biology 2007-05-23 Anders Eriksson , Kristian Lindgren

The processes and mechanisms underlying the origin and maintenance of biological diversity have long been of central importance in ecology and evolution. The competitive exclusion principle states that the number of coexisting species is…

Populations and Evolution · Quantitative Biology 2020-12-02 Michael Doebeli , Eduardo Cancino Jaque , Iaroslav Ispolatov

Motivated by modeling the dynamics of a population living in a flowing medium where the environmental factors are random in space, we have studied an asymmetric variant of the one-dimensional contact process, where the quenched random…

Disordered Systems and Neural Networks · Physics 2015-06-16 Róbert Juhász

Geographic ranges of communities of species evolve in response to environmental, ecological, and evolutionary forces. Understanding the effects of these forces on species' range dynamics is a major goal of spatial ecology. Previous…

Populations and Evolution · Quantitative Biology 2022-02-02 Farshad Shirani , Judith R. Miller

We consider a fixed size population that undergoes an evolutionary adaptation in the weak mutuation rate limit, which we model as a biased Langevin process in the genotype space. We show analytically and numerically that, if the fitness…

Populations and Evolution · Quantitative Biology 2014-02-04 Jakub Otwinowski , Sorin Tanase-Nicola , Ilya Nemenman