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We present a novel mathematical model of heterogeneous cell proliferation where the total population consists of a subpopulation of slow-proliferating cells and a subpopulation of fast-proliferating cells. The model incorporates two…

Cell Behavior · Quantitative Biology 2021-11-04 Sean T. Vittadello , Scott W. McCue , Gency Gunasingh , Nikolas K. Haass , Matthew J. Simpson

Time-varying networks describe a wide array of systems whose constituents and interactions evolve over time. They are defined by an ordered stream of interactions between nodes, yet they are often represented in terms of a sequence of…

Statistical Mechanics · Physics 2013-10-23 Bruno Ribeiro , Nicola Perra , Andrea Baronchelli

The metabolic networks are very well characterized for a large set of organisms, a unique case in within the large-scale biological networks. For this reason they provide a a very interesting framework for the construction of analytically…

Molecular Networks · Quantitative Biology 2007-05-23 Ginestra Bianconi , Riccardo Zecchina

This article investigates emergence and complexity in complex systems that can share information on a network. To this end, we use a theoretical approach from information theory, computability theory, and complex networks. One key studied…

Information Theory · Computer Science 2019-03-20 Felipe S. Abrahão , Klaus Wehmuth , Artur Ziviani

In this paper we investigate networks whose evolution is governed by the interaction of a random assembly process and an optimization process. In the first process, new nodes are added one at a time and form connections to randomly selected…

Disordered Systems and Neural Networks · Physics 2011-05-16 Markus Brede

Evolutionary dynamics and patterns of molecular evolution are strongly influenced by selection on linked regions of the genome, but our quantitative understanding of these effects remains incomplete. Recent work has focused on predicting…

Populations and Evolution · Quantitative Biology 2013-05-29 Benjamin H. Good , Michael M. Desai

In the paper, we study fluctuations over several ensembles of maximum-entropy random networks. We derive several fluctuation-dissipation relations characterizing susceptibilities of different networks to changes in external fields. In the…

Disordered Systems and Neural Networks · Physics 2009-11-11 Agata Fronczak , Piotr Fronczak , Janusz A. Holyst

Research on the vulnerability of electric networks with a complex network approach has produced significant results in the last decade, especially for transmission networks. These studies have shown that there are causal relations between…

Physics and Society · Physics 2024-09-11 Bálint Hartmann , Tamás Soha , Michelle T. Cirunay , Tímea Erdei

The control of complex systems is an ongoing challenge of complexity research. Recent advances using concepts of structural control deduce a wide range of control related properties from the network representation of complex systems. Here,…

Statistical Mechanics · Physics 2013-12-31 Márton Pósfai , Philipp Hövel

A general population evolution model is considered. Any individual of the population is characterized by its score. Certain general conditions are assumed concerning the number of the individuals and their scores. Asymptotic theorems are…

Probability · Mathematics 2016-04-07 I. Fazekas , Cs. Noszály , A. Perecsényi

In this paper, we propose an evolving network model growing fast in units of module, based on the analysis of the evolution characteristics in real complex networks. Each module is a small-world network containing several interconnected…

Physics and Society · Physics 2011-10-11 Zou Zhi-Yun , Liu Peng , Lei Li , Gao Jian-Zhi

Natural selection explains how life has evolved over millions of years from more primitive forms. The speed at which this happens, however, has sometimes defied formal explanations when based on random (uniformly distributed) mutations.…

Neural and Evolutionary Computing · Computer Science 2018-06-22 Santiago Hernández-Orozco , Narsis A. Kiani , Hector Zenil

Networks describing the interaction of the elements that constitute a complex system grow and develop via a number of different mechanisms, such as the addition and deletion of nodes, the addition and deletion of edges, as well as the…

Molecular Networks · Quantitative Biology 2010-06-09 Arend Hintze , Christoph Adami

We analyse a collection of empirical networks in a wide spectrum of disciplines and show that strong non-normality is ubiquitous in network science. Dynamical processes evolving on non-normal networks exhibit a peculiar behaviour, as…

Adaptation and Self-Organizing Systems · Physics 2018-11-09 Malbor Asllani , Renaud Lambiotte , Timoteo Carletti

Superslow diffusion, i.e., the long-time diffusion of particles whose mean-square displacement (variance) grows slower than any power of time, is studied in the framework of the decoupled continuous-time random walk model. We show that this…

Statistical Mechanics · Physics 2010-11-24 S. I. Denisov , H. Kantz

Dynamic optimisation occurs in a variety of real-world problems. To tackle these problems, evolutionary algorithms have been extensively used due to their effectiveness and minimum design effort. However, for dynamic problems, extra…

Neural and Evolutionary Computing · Computer Science 2020-08-11 Maryam Hasani Shoreh , Renato Hermoza Aragonés , Frank Neumann

Both evolution and ecology have long been concerned with the impact of variable environmental conditions on observed levels of genetic diversity within and between species. We model the evolution of a quantitative trait under selection that…

Populations and Evolution · Quantitative Biology 2014-11-17 Hannes Svardal , Claus Rueffler , Joachim Hermisson

Evolution produces complex and structured networks of interacting components in chemical, biological, and social systems. We describe a simple mathematical model for the evolution of an idealized chemical system to study how a network of…

Adaptation and Self-Organizing Systems · Physics 2014-03-05 Sanjay Jain , Sandeep Krishna

With a view to connecting random mutation on the molecular level to punctuated equilibrium behavior on the phenotype level, we propose a new model for biological evolution, which incorporates random mutation and natural selection. In this…

Condensed Matter · Physics 2009-10-28 M. Y. Choi , H. Y. Lee , D. Kim , S. H. Park

Mathematical models of motility are often based on random-walk descriptions of discrete individuals that can move according to certain rules. It is usually the case that large masses concentrated in small regions of space have a great…

Physics and Society · Physics 2022-11-23 Carles Falcó