Related papers: Global and regional brain metabolic scaling and it…
To study information processing in the brain, neuroscientists manipulate experimental stimuli while recording participant brain activity. They can then use encoding models to find out which brain "zone" (e.g. which region of interest,…
Life presents fascinating examples of self-organization and emergent phenomena. In multi-cellular organisms, a multitude of cells interact to form and maintain highly complex body plans of well-defined size. In this thesis, we investigate…
Artificial and biological systems may evolve similar computational solutions despite fundamental differences in architecture and learning mechanisms -- a form of convergent evolution. We demonstrate this phenomenon through large-scale…
Current computers operate at enormous speeds of ~10^13 bits/s, but their principle of sequential logic operation has remained unchanged since the 1950s. Though our brain is much slower on a per-neuron base (~10^3 firings/s), it is capable…
The group of large aquatic mammals has representatives being the largest living beings on earth, surpassing the weight and size of dinosaurs. In this paper, we present some empirical evidence and a mathematical model to argue that fat…
To maintain coherence in language, the brain must satisfy key competing temporal demands: the gradual accumulation of meaning across extended context (drift) and the rapid reconfiguration of representations at event boundaries (shift). How…
Microbes require several complex organic molecules for growth. A species may obtain a required factor by taking up molecules released by other species or by synthesizing the molecule. The patterns of uptake and synthesis set a flow of…
The evolution of biological brains has always been contingent on their embodiment within their respective environments, in which survival required appropriate navigation and manipulation skills. Studying such interactions thus represents an…
The anatomically layered structure of a human brain results in leveled functions. In all these levels of different functions, comparison, feedback and imitation are the universal and crucial mechanisms. Languages, symbols and tools play key…
The brain is not only constrained by energy needed to fuel computation, but it is also constrained by energy needed to form memories. Experiments have shown that learning simple conditioning tasks already carries a significant metabolic…
Brains have evolved diverse neurons with varying morphologies and dynamics that impact temporal information processing. In contrast, most neural network models use homogeneous units that vary only in spatial parameters (weights and biases).…
To understand Working of Human Brain measurements related to the brain function are required. These measurements should be possibly non-invasive. Brain should be disturbed as less as possible during the measurement. Integration of various…
Scale does not uniformly improve reasoning - it restructures it. Analyzing 25,000+ chain-of-thought trajectories across four domains (Law, Science, Code, Math) and two scales (8B, 70B parameters), we discover that neural scaling laws…
Starting from the morphological-functional assumption of the fractal brain, a mathematical model is given by activating brain non-differentiable dynamics through the determinism-nondeterminism inference of the responsible mechanisms. The…
Respiration measurements of whole tree plants have been reported that give evidence that the relative per volume/mass unit respiration decreases with increase of tree body size. In this study, based on the available data published a…
Standard Spiking Neural Network (SNN) models typically neglect metabolic constraints, treating neurons as energetically unconstrained components. We bridge this gap by implementing a conductance-based leaky integrate-and-fire (gLIF)…
We address the problem of estimating how different parts of the brain develop and change throughout the lifespan, and how these trajectories are affected by genetic and environmental factors. Estimation of these lifespan trajectories is…
High-throughput experimental techniques and bioinformatics tools make it possible to obtain reconstructions of the metabolism of microbial species. Combined with mathematical frameworks such as flux balance analysis, which assumes that…
A coupled map is suggested to investigate various spatial or temporal designs in biology: Several cells (or tissues) in an organ are considered as connected to each other in terms of some molecular diffusions or electrical potential…
Cell cultures exhibit rich and complex behaviors driven by dynamic metabolic interactions among cells. In this work, we present a model that captures these interactions through a framework inspired by statistical mechanics. Using Monte…