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Genome-wide association analysis has generated much discussion about how to preserve power to detect signals despite the detrimental effect of multiple testing on power. We develop a weighted multiple testing procedure that facilitates the…

Statistics Theory · Mathematics 2007-06-13 Kathryn Roeder , Bernie Devlin , Larry Wasserman

Subsampling algorithms for various parametric regression models with massive data have been extensively investigated in recent years. However, all existing studies on subsampling heavily rely on clean massive data. In practical…

Statistics Theory · Mathematics 2025-06-11 Jiangshan Ju , Mingqiu Wang , Shengli Zhao

We consider statistical procedures for hypothesis testing of real valued functionals of matched pairs with missing values. In order to improve the accuracy of existing methods, we propose a novel multiplication combination procedure.…

Statistics Theory · Mathematics 2018-01-29 Lubna Amro , Frank Konietschke , Markus Pauly

We consider the problem of testing positively dependent multiple hypotheses assuming that a prior information about the dependence structure is available. We propose two-step multiple comparisons procedures that exploit the prior…

This study uses stacked generalization, which is a two-step process of combining machine learning methods, called meta or super learners, for improving the performance of algorithms in step one (by minimizing the error rate of each…

Machine Learning · Computer Science 2020-04-07 Kathleen Kerwin , Nathaniel D. Bastian

Certifying whether an arbitrary quantum system is entangled or not, is, in general, an NP-hard problem. Though various necessary and sufficient conditions have already been explored in this regard for lower dimensional systems, it is hard…

Quantum Physics · Physics 2024-12-03 Sanuja D. Mohanty , Ram N. Patro , Pradyut K. Biswal , Biswajit Pradhan , Sk Sazim

As the size, complexity, and availability of data continues to grow, scientists are increasingly relying upon black-box learning algorithms that can often provide accurate predictions with minimal a priori model specifications. Tools like…

Machine Learning · Statistics 2020-11-10 Lucas Mentch , Siyu Zhou

In this paper we have updated the hypothesis testing framework by drawing upon modern computational power and classification models from machine learning. We show that a simple classification algorithm such as a boosted decision stump can…

Econometrics · Economics 2021-03-03 Gary Cornwall , Jeff Chen , Beau Sauley

Model averaging techniques based on resampling methods (such as bootstrapping or subsampling) have been utilized across many areas of statistics, often with the explicit goal of promoting stability in the resulting output. We provide a…

Statistics Theory · Mathematics 2024-05-28 Jake A. Soloff , Rina Foygel Barber , Rebecca Willett

The aim of this work is to propose a meta-algorithm for automatic classification in the presence of discrete binary classes. Classifier learning in the presence of overlapping class distributions is a challenging problem in machine…

Machine Learning · Statistics 2020-01-22 Vidhi Lalchand

A fundamental task in machine learning and related fields is to perform inference on Bayesian networks. Since exact inference takes exponential time in general, a variety of approximate methods are used. Gibbs sampling is one of the most…

Machine Learning · Computer Science 2015-11-23 Daniel Seita , Haoyu Chen , John Canny

This article introduces subbagging (subsample aggregating) estimation approaches for big data analysis with memory constraints of computers. Specifically, for the whole dataset with size $N$, $m_N$ subsamples are randomly drawn, and each…

Methodology · Statistics 2021-03-05 Tao Zou , Xian Li , Xuan Liang , Hansheng Wang

Empirical analysis serves as an important complement to theoretical analysis for studying practical Bayesian optimization. Often empirical insights expose strengths and weaknesses inaccessible to theoretical analysis. We define two metrics…

Machine Learning · Computer Science 2016-04-01 Ian Dewancker , Michael McCourt , Scott Clark , Patrick Hayes , Alexandra Johnson , George Ke

Statistical dependence between hypotheses poses a significant challenge to the stability of large scale multiple hypotheses testing. Ignoring it often results in an unacceptably large spread in the false positive proportion even though the…

Methodology · Statistics 2018-10-15 Sairam Rayaprolu , Zhiyi Chi

Large-scale multiple testing is a fundamental problem in high dimensional statistical inference. It is increasingly common that various types of auxiliary information, reflecting the structural relationship among the hypotheses, are…

Methodology · Statistics 2021-10-07 Hongyuan Cao , Jun Chen , Xianyang Zhang

Businesses frequently run online controlled experiments (i.e., A/B tests) to learn about the effect of an intervention on multiple business metrics. To account for multiple hypothesis testing, multiple metrics are commonly aggregated into a…

Methodology · Statistics 2026-01-22 Luke Hagar , Nathaniel T. Stevens

Predictions from machine learning algorithms can vary across random seeds, inducing instability in downstream debiased machine learning estimators. We formalize random seed stability via a concentration condition and prove that subbagging…

Methodology · Statistics 2026-04-21 Nicholas Williams , Alejandro Schuler

Bayesian inference is attractive for its coherence and good frequentist properties. However, it is a common experience that eliciting a honest prior may be difficult and, in practice, people often take an {\em empirical Bayes} approach,…

Statistics Theory · Mathematics 2012-04-09 Sonia Petrone , Judith Rousseau , Catia Scricciolo

Statistical hypothesis testing serves as statistical evidence for scientific innovation. However, if the reported results are intentionally biased, hypothesis testing no longer controls the rate of false discovery. In particular, we study…

Methodology · Statistics 2018-10-12 Junpei Komiyama , Takanori Maehara

For machine learning task, lacking sufficient samples mean the trained model has low confidence to approach the ground truth function. Until recently, after the generative adversarial networks (GAN) had been proposed, we see the hope of…

Machine Learning · Computer Science 2019-05-22 Mengxiao Hu , Jinlong Li