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Markov chain Monte Carlo (MCMC) methods are widely used in machine learning. One of the major problems with MCMC is the question of how to design chains that mix fast over the whole state space; in particular, how to select the parameters…

Machine Learning · Computer Science 2019-07-16 Kiarash Shaloudegi , András György

Remarkable progress has been made on automated reasoning with natural text, by using Language Models (LMs) and methods such as Chain-of-Thought and Selection-Inference. These techniques search for proofs in the forward direction from axioms…

Artificial Intelligence · Computer Science 2023-05-30 Mehran Kazemi , Najoung Kim , Deepti Bhatia , Xin Xu , Deepak Ramachandran

In past work (Onokpasa, Wild, Wong, DCC 2023), we showed that (a) for joint compression of RNA sequence and structure, stochastic context-free grammars are the best known compressors and (b) that grammars which have better compression…

Data Structures and Algorithms · Computer Science 2024-01-31 Evarista Onokpasa , Sebastian Wild , Prudence W. H. Wong

Sequence modeling with neural networks has lead to powerful models of symbolic music data. We address the problem of exploiting these models to reach creative musical goals, by combining with human input. To this end we generalise previous…

Artificial Intelligence · Computer Science 2017-10-03 Christian Walder , Dongwoo Kim

Feature models are widely used to capture the configuration space of software systems. Although automated reasoning has been studied for detecting problematic features and supporting configuration tasks, significantly less attention has…

Software Engineering · Computer Science 2026-03-18 Jose Manuel Sanchez , Miguel Angel Olivero , Ruben Heradio , Luis Cambelo , David Fernandez-Amoros

We propose a new approach for estimating the finite dimensional transition matrix of a Markov chain using a large number of independent sample paths observed at random times. The sample paths may be observed as few as two times, and the…

Methodology · Statistics 2025-05-20 Daphne Aurouet , Valentin Patilea

In this paper, it is presented a methodology for implementing arbitrarily constructed time-homogenous Markov chains with biochemical systems. Not only discrete but also continuous-time Markov chains are allowed to be computed. By employing…

Molecular Networks · Quantitative Biology 2018-02-16 Chuan Zhang , Ziyuan Shen , Wei Wei , Jing Zhao , Zaichen Zhang , Xiaohu You

Recently, evolving networks are becoming a suitable form to model many real-world complex systems, due to their peculiarities to represent the systems and their constituting entities, the interactions between the entities and the…

Artificial Intelligence · Computer Science 2017-09-21 Angelo Impedovo , Corrado Loglisci , Michelangelo Ceci

Mutational signatures describe the pattern of mutations over the different mutation types. Each mutation type is determined by a base substitution and the flanking nucleotides to the left and right of that base substitution. Due to the…

Populations and Evolution · Quantitative Biology 2026-04-24 Ragnhild Laursen , Marta Pelizzola , Lasse Maretty , Asger Hobolth

Online music databases have increased signicantly as a consequence of the rapid growth of the Internet and digital audio, requiring the development of faster and more efficient tools for music content analysis. Musical genres are widely…

Data Analysis, Statistics and Probability · Physics 2015-05-14 Debora C. Correa , Jose H. Saito , Luciano da F. Costa

Microbiological systems evolve to fulfill their tasks with maximal efficiency. The immune system is a remarkable example, where self-non self distinction is accomplished by means of molecular interaction between self proteins and antigens,…

Cell Behavior · Quantitative Biology 2013-08-26 Marcio Argollo de Menezes , Edgardo Brigatti , Veit Schwämmle

This talk will review a little over a decade's research on applying certain stochastic models to biological sequence analysis. The models themselves have a longer history, going back over 30 years, although many novel variants have arisen…

Probability · Mathematics 2007-05-23 T. P. Speed

Patterns are fundamental to human cognition, enabling the recognition of structure and regularity across diverse domains. In this work, we focus on structural repeats, patterns that arise from the repetition of hierarchical relations within…

Computation and Language · Computer Science 2025-04-15 Zeng Ren , Xinyi Guan , Martin Rohrmeier

We consider the analysis of sets of categorical sequences consisting of piecewise homogeneous Markov segments. The sequences are assumed to be governed by a common underlying process with segments occurring in the same order for each…

Methodology · Statistics 2015-04-08 Petter Arnesen , Tracy Holsclaw , Padhraic Smyth

Characterizing whether a Markov process of discrete random variables has an homogeneous continuous-time realization is a hard problem. In practice, this problem reduces to deciding when a given Markov matrix can be written as the…

Probability · Mathematics 2021-06-23 Marta Casanellas , Jesús Fernández-Sánchez , Jordi Roca-Lacostena

The interaction between proteins and DNA is a key driving force in a significant number of biological processes such as transcriptional regulation, repair, recombination, splicing, and DNA modification. The identification of DNA-binding…

Quantitative Methods · Quantitative Biology 2017-05-10 Hamid Reza Hassanzadeh , Pushkar Kolhe , Charles L. Isbell , May D. Wang

The convergence, convergence rate and expected hitting time play fundamental roles in the analysis of randomised search heuristics. This paper presents a unified Markov chain approach to studying them. Using the approach, the sufficient and…

Optimization and Control · Mathematics 2013-12-10 Jun He , Feidun He , Xin Yao

Generative statistical models of chord sequences play crucial roles in music processing. To capture syntactic similarities among certain chords (e.g. in C major key, between G and G7 and between F and Dm), we study hidden Markov models and…

Artificial Intelligence · Computer Science 2018-03-05 Hiroaki Tsushima , Eita Nakamura , Katsutoshi Itoyama , Kazuyoshi Yoshii

Networks are a fundamental tool for modeling complex systems in a variety of domains including social and communication networks as well as biology and neuroscience. Small subgraph patterns in networks, called network motifs, are crucial to…

Social and Information Networks · Computer Science 2018-01-08 Ashwin Paranjape , Austin R. Benson , Jure Leskovec

This paper shows how a folded Markov chain network can be applied to the problem of processing data from multiple sensors, with an emphasis on the special case of 2 sensors. It is necessary to design the network so that it can transform a…

Neural and Evolutionary Computing · Computer Science 2010-12-21 S P Luttrell