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During development, embryos perform a mesmerizing choreography, which is crucial for the correct shaping, positioning and function of all organs. The cellular properties powering animal morphogenesis have been the focus of much attention.…

Cell Behavior · Quantitative Biology 2019-07-25 Markus Schliffka , Jean-Léon Maître

The spontaneous generation of electrical activity underpins a number of essential physiological processes, and is observed even in tissues where specialized pacemaker cells have not been identified. The emergence of periodic oscillations in…

Adaptation and Self-Organizing Systems · Physics 2022-02-01 Ria Ghosh , Shakti N. Menon

Collective cell motions underlie structure formation during embryonic development. Tissues exhibit emergent multicellular characteristics such as jamming, rigidity transitions, and glassy dynamics, but there remain questions about how those…

Biological Physics · Physics 2023-12-13 Evan Thomas , Sevan Hopyan

Various microorganisms and some mammalian cells are able to swim in viscous fluids by performing nonreciprocal body deformations, such as rotating attached flagella or by distorting their entire body. In order to perform chemotaxis, i.e. to…

Biological Physics · Physics 2021-05-06 Benedikt Hartl , Maximilian Hübl , Gerhard Kahl , Andreas Zöttl

Synchronized oscillations in networks of inhibitory and excitatory coupled bursting neurons are common in a variety of neural systems from central pattern generators to human brain circuits. One example of the latter is the subcortical…

Neurons and Cognition · Quantitative Biology 2011-09-21 Choongseok Park , Leonid L. Rubchinsky

A basal animal model is described as an organism similar to a Limpet that is attached to the sea floor living in a reproductive community. Its brain model uses logic cells (gates) to create a high frequency spike generator. Addition logic…

Other Quantitative Biology · Quantitative Biology 2016-12-19 Robert Alan Brown

Biological systems are majorly dependent on their property of bistability in order to exhibit nongenetic heterogeneity in terms of cellular morphology and physiology. Spatial patterns of phenotypically heterogeneous cells, arising due to…

Quantitative Methods · Quantitative Biology 2023-01-25 Priya Chakraborty , Ushasi Roy , Mohit K. Jolly , Sayantari Ghosh

Spatially localized oscillations in periodically forced systems are intriguing phenomena. They may occur in spatially homogeneous media (oscillons), but quite often emerge in heterogeneous media, such as the auditory system, where localized…

Pattern Formation and Solitons · Physics 2020-04-21 Yuval Edri , Ehud Meron , Arik Yochelis

Resonance transitions between the Zeeman sublevels of optically-polarized Rb atoms traveling through a spatially periodic magnetic field are investigated in a radio-frequency (rf) range of sub-MHz. The atomic motion induces the resonance…

Atomic Physics · Physics 2008-10-21 Atsushi Hatakeyama

Spatial patterns in the early fruit fly embryo emerge from a network of interactions among transcription factors, the gap genes, driven by maternal inputs. Such networks can exhibit many qualitatively different behaviors, separated by…

Molecular Networks · Quantitative Biology 2015-06-17 Dmitry Krotov , Julien O. Dubuis , Thomas Gregor , William Bialek

In embryonic development, programmed cell shape changes are essential for building functional organs, but in many cases the mechanisms that precisely regulate these changes remain unknown. We propose that fluid-like drag forces generated by…

Biological Physics · Physics 2019-01-03 Gonca Erdemci-Tandogan , Madeline J. Clark , Jeffrey D. Amack , M. Lisa Manning

A lattice-indexed family of stochastic processes has quasi-cycle oscillations if its otherwise-damped oscillations are sustained by noise. Such a family performs the reaction part of a discrete stochastic reaction-diffusion system when we…

Neurons and Cognition · Quantitative Biology 2019-09-25 Priscilla E. Greenwood , Lawrence M. Ward

We demonstrate that demographic noise can induce persistent spatial pattern formation and temporal oscillations in the Levin-Segel predator-prey model for plankton-herbivore population dynamics. Although the model exhibits a Turing…

Populations and Evolution · Quantitative Biology 2015-05-13 Thomas Butler , Nigel Goldenfeld

In many adult tissues, stem cells and differentiated cells are not homogeneously distributed : stem cells are arranged in periodic "niches", and differentiated cells are constantly produced and migrate out of these niches. In this article,…

Biological Physics · Physics 2016-03-23 Edouard Hannezo , Alice Coucke , Jean-François Joanny

We argue that embryological morphogenesis provides a model of how massive swarms of microscopic agents can be coordinated to assemble complex, multiscale hierarchical structures. This is accomplished by understanding natural morphogenetic…

Multiagent Systems · Computer Science 2019-08-26 Bruce J. MacLennan , Allen C. McBride

Spatio-temporal signals arising from event-driven biological processes, such as surface electromyography (sEMG), exhibit asynchronous and highly structured activation patterns that are challenging to model using conventional discrete or…

Machine Learning · Computer Science 2026-05-05 Magnus Bengtsson

Artificial intelligence research to a great degree focuses on the brain and behaviors that the brain generates. But the brain, an extremely complex structure resulting from millions of years of evolution, can be viewed as a solution to…

Neurons and Cognition · Quantitative Biology 2017-03-07 Thomas E. Portegys

Neural dynamics underlie behaviors from memory to sleep, yet identifying mechanisms for higher-order phenomena (e.g., social interaction) is experimentally challenging. Existing whole-brain models often fail to scale to single-neuron…

Neurons and Cognition · Quantitative Biology 2025-11-03 Sam Fatehmanesh Vegas , Matt Thomson , James Gornet , David Prober

Synchronization in neural system plays an important role in many brain functions. Synchronization in the gamma frequency band (30Hz-100Hz) is involved in a variety of cognitive phenomena; abnormalities of the gamma synchronization are found…

Neurons and Cognition · Quantitative Biology 2021-04-26 Quynh-Anh Nguyen , Leonid L Rubchinsky

Oscillations are omnipresent in neural population signals, like multi-unit recordings, EEG/MEG, and the local field potential. They have been linked to the population firing rate of neurons, with individual neurons firing in a…

Neurons and Cognition · Quantitative Biology 2017-02-08 Hannah Bos , Markus Diesmann , Moritz Helias
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