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Evaluation of artificial intelligence (AI) models for low-dose CT lung cancer screening is limited by heterogeneous datasets, annotation standards, and evaluation protocols, making performance difficult to compare and translate across…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Fakrul Islam Tushar , Avivah Wang , Lavsen Dahal , Ehsan Samei , Michael R. Harowicz , Jayashree Kalpathy-Cramer , Kyle J. Lafata , Tina D. Tailor , Cynthia Rudin , Joseph Y. Lo

Objectives: To compare artificial intelligence (AI) as a second reader in detecting lung nodules on chest X-rays (CXR) versus radiologists of two binational institutions, and to evaluate AI performance when using two different modes:…

While deep learning methods are increasingly being applied to tasks such as computer-aided diagnosis, these models are difficult to interpret, do not incorporate prior domain knowledge, and are often considered as a "black-box." The lack of…

Computer Vision and Pattern Recognition · Computer Science 2018-06-05 Shiwen Shen , Simon X. Han , Denise R. Aberle , Alex A. T. Bui , Willliam Hsu

Lung nodule malignancy prediction is an essential step in the early diagnosis of lung cancer. Besides the difficulties commonly discussed, the challenges of this task also come from the ambiguous labels provided by annotators, since deep…

Image and Video Processing · Electrical Eng. & Systems 2021-04-26 Zehui Liao , Yutong Xie , Shishuai Hu , Yong Xia

We propose iW-Net, a deep learning model that allows for both automatic and interactive segmentation of lung nodules in computed tomography images. iW-Net is composed of two blocks: the first one provides an automatic segmentation and the…

Computer Vision and Pattern Recognition · Computer Science 2018-12-03 Guilherme Aresta , Colin Jacobs , Teresa Araújo , António Cunha , Isabel Ramos , Bram van Ginneken , Aurélio Campilho

Detection and classification of pulmonary nodules is a challenge in medical image analysis due to the variety of shapes and sizes of nodules and their high concealment. Despite the success of traditional deep learning methods in image…

Image and Video Processing · Electrical Eng. & Systems 2025-02-28 Junji Lin , Yi Zhang , Yunyue Pan , Yuli Chen , Chengchang Pan , Honggang Qi

Pulmonary diseases are a public health problem that requires accurate and fast diagnostic techniques. In this paper, a method based on convolutional neural networks (CNN), Data Augmentation, ResNet50 and Vision Transformers (ViT) is…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Pablo Ramirez Amador , Dinarle Milagro Ortega , Arnold Cesarano

A number of studies on lung nodule classification lack clinical/biological interpretations of the features extracted by convolutional neural network (CNN). The methods like class activation mapping (CAM) and gradient-based CAM (Grad-CAM)…

Computer Vision and Pattern Recognition · Computer Science 2019-12-18 Yiming Lei , Yukun Tian , Hongming Shan , Junping Zhang , Ge Wang , Mannudeep Kalra

In the last two decades Computer Aided Diagnostics (CAD) systems were developed to help radiologists analyze screening mammograms. The benefits of current CAD technologies appear to be contradictory and they should be improved to be…

Computer Vision and Pattern Recognition · Computer Science 2017-11-10 Dezső Ribli , Anna Horváth , Zsuzsa Unger , Péter Pollner , István Csabai

Accurate Computer-Assisted Diagnosis, relying on large-scale annotated pathological images, can alleviate the risk of overlooking the diagnosis. Unfortunately, in medical imaging, most available datasets are small/fragmented. To tackle…

Computer Vision and Pattern Recognition · Computer Science 2019-08-14 Changhee Han , Yoshiro Kitamura , Akira Kudo , Akimichi Ichinose , Leonardo Rundo , Yujiro Furukawa , Kazuki Umemoto , Yuanzhong Li , Hideki Nakayama

Lung nodules can be an alarming precursor to potential lung cancer. Missed nodule detections during chest radiograph analysis remains a common challenge among thoracic radiologists. In this work, we present a multi-task lung nodule…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Chen-Han Tsai , Yu-Shao Peng

Lung cancer is one of the most commonly diagnosed cancers, and early diagnosis is critical because the survival rate declines sharply once the disease progresses to advanced stages. However, achieving an early diagnosis remains challenging,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Yutong Wu , Yifan Wang , Qining Zhang , Chuan Zhou , Lei Ying

Nodule malignancy assessment is a complex, time-consuming and error-prone task. Current clinical practice requires measuring changes in size and density of the nodule at different time-points. State of the art solutions rely on 3D…

Image and Video Processing · Electrical Eng. & Systems 2020-05-27 Xavier Rafael-Palou , Anton Aubanell , Ilaria Bonavita , Mario Ceresa , Gemma Piella , Vicent Ribas , Miguel A. González Ballester

We present a fully automated method for top-down segmentation of the pulmonary arterial tree in low-dose thoracic CT images. The main basal pulmonary arteries are identified near the lung hilum by searching for candidate vessels adjacent to…

Computer Vision and Pattern Recognition · Computer Science 2011-06-28 Jeremiah Wala , Sergei Fotin , Jaesung Lee , Artit Jirapatnakul , Alberto Biancardi , Anthony Reeves

The CALMA (Computer Assisted Library for MAmmography) project is a five years plan developed in a physics research frame in collaboration between INFN (Istituto Nazionale di Fisica Nucleare) and many Italian hospitals. At present a large…

Medical Physics · Physics 2009-11-10 A. Lauria , R. Palmiero , G. Forni , P. Cerello , B. Golosio , F. Fauci , R. Magro , G. Raso , S. Tangaro , P. L. Indovina

Background: Artificial intelligence (AI) assisted lung nodule detection systems are increasingly deployed in clinical settings without site-specific validation. Performance reported under benchmark conditions may not reflect real-world…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Daniel Soliman

Lung nodules are commonly missed in chest radiographs. We propose and evaluate P-AnoGAN, an unsupervised anomaly detection approach for lung nodules in radiographs. P-AnoGAN modifies the fast anomaly detection generative adversarial network…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Nitish Bhatt , David Ramon Prados , Nedim Hodzic , Christos Karanassios , H. R. Tizhoosh

Lung adenocarcinoma (LUAD) is a morphologically heterogeneous disease, characterized by five primary histological growth patterns. The classification of such patterns is crucial due to their direct relation to prognosis but the high…

Image and Video Processing · Electrical Eng. & Systems 2025-01-15 Arwa Al-Rubaian , Gozde N. Gunesli , Wajd A. Althakfi , Ayesha Azam , David Snead , Nasir M. Rajpoot , Shan E Ahmed Raza

The standard non-invasive imaging technique used to assess the severity and extent of Coronary Artery Disease (CAD) is Coronary Computed Tomography Angiography (CCTA). However, manual grading of each patient's CCTA according to the…

AI models for lung cancer screening are limited by data scarcity, impacting generalizability and clinical applicability. Generative models address this issue but are constrained by training data variability. We introduce SYN-LUNGS, a…

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