Tissues and Organs
Understanding the emergence of biological structures and their changes is a complex problem. On a biochemical level, it is based on gene regulatory networks (GRN) consisting on interactions between the genes responsible for cell…
We present the validation of a recent fractional mathematical model for erythrocyte sedimentation proposed by Sharma et al. \cite{GMR}. The model uses a Caputo fractional derivative to build a time fractional diffusion equation suitable to…
Chondrocytes are described as one cell population in different cartilage types. The auricular cartilage in mouse and rat contains unique chondrocytes similar in morphology to white adipocytes and known as lipochondrocytes. Lipochondrocytes…
In lens cataract, the clouding change in lens leads to a decline of transparency of part of the lens. There are three types of senile cataract: cortical cataract, nuclear cataract, and posterior/anterior sub-capsular cataract. The most…
Age spots are the brown spots that develop in the skin but change in color and shape with time. To understand the mechanism of development of age spots, characteristics of age spots are analyzed by Misrepair mechanism, a mechanism…
The liver of reptiles is considered an important study model for the interaction between environment and hepatic tissue. Little is known about the histology of the liver of reptiles. The aim of the current study was to elucidate the…
Currently, diagnosis of skin diseases is based primarily on visual pattern recognition skills and expertise of the physician observing the lesion. Even though dermatologists are trained to recognize patterns of morphology, it is still a…
In this paper, we study a phase-space analysis of a mathematical model of tumor growth with an immune response. Mathematical analysis of the model equations with multipoint initial condition, regarding to dissipativity, boundedness of…
Staphylococcus aureus responsible for nosocomial infections is a significant threat to the public health. The increasing resistance of S.aureus to various antibiotics has drawn it to a prime focus for research on designing an appropriate…
The accurate assessment of White matter hyperintensities (WMH) burden is of crucial importance for epidemiological studies to determine association between WMHs, cognitive and clinical data. The manual delineation of WMHs is tedious, costly…
Recent experimental work on the nephrotoxicity of contaminants in drinking water using laboratory mice, motivated by the need to understand the origin of chronic kidney disease of unknown aetiology is examined within our understanding of…
The mortality rate of many complex multicellular organisms increase with age, which suggests that net aging damage is accumulative, despite remodeling processes. But how exactly do little mishaps in the cellular level accumulate and spread…
Understanding cell fate patterning and morphogenesis in the mammalian embryo remains a formidable challenge. Recently, in vivo models based on embryonic stem cells (ESCs) have emerged as complementary methods to quantitatively dissect the…
During the last decades, medical observations and multiscale data concerning tumor growth are mounting. At the same time, contemporary imaging techniques well established in clinical practice, provide a variety of information on real-time,…
Aims. The objective of this paper is to determine the incidence of ophthalmic disease potentially leading to optic nerve disease in Middle Tennessee. Methods. We use a retrospective population-based incidence study design focusing on the…
We consider the mechanisms by which folds, or sulci (troughs) and gyri (crests), develop in the brain. This feature, common to many gyrencephalic species including humans, has attracted recent attention from soft matter physicists. It…
Objectives: To obtain a better estimate of the mortality of individuals suffering from blunt force trauma, including co-morbidity. Methodology: The Injury severity Score (ISS) is the default world standard for assessing the severity of…
Background: Salinity is one of the major abiotic stresses affecting plant production in arid and semi-arid regions. It causes reduction of cultivable area and combined with other factors, presents a serious threat to food stability in these…
We introduce a continuous modeling approach which combines elastic responds of the trabecular bone structure, the concentration of signaling molecules within the bone and a mechanism how this concentration at the bone surface is used for…
Although cirrhosis is a key risk factor for the development of hepatocellular carcinoma (HCC), mounting evidence indicates that in a subset of patients presenting with non-alcoholic steatohepatitis (NASH), HCC manifests in the absence of…