Biological Physics
Proteins typically undergo conformational dynamics on the microsecond to millisecond timescale as they perform their function, which is much faster than the time-resolution of cryo-electron microscopy and has thus prevented real-time…
Cell migration, which can be significantly affected by intracellular signaling pathways (ICSP) and extracellular matrix (ECM), plays a crucial role in many physiological and pathological processes. The efficiency of cell migration, which is…
Reaction-diffusion waves have long been used to describe the growth and spread of populations undergoing a spatial range expansion. Such waves are generally classed as either pulled, where the dynamics are driven by the very tip of the…
We address the well-known limitation of the Huxley and Simmons 1971 (HS) model. It is a statement that at physiological value of stiffness in the actomyosin complex, the distribution of the myosin motors becomes microscopically uniform (all…
Being the polymorphs of calcium carbonate (CaCO3), vaterite and calcite have attracted a great deal of attention as promising biomaterials for drug delivery and tissue engineering applications. Furthermore, they are important biogenic…
Using simple radiofrequency (RF) instrumentation, we detect spontaneous RF emission from Drosophila immersed in a magnetic field within a waveguide or a shielded RF resonator. Remarkably, the RF emissions are abolished by chloroform…
Nuclei import and export proteins, including cell cycle regulators. These import-export processes are modulated periodically by the cell cycle, for example due to the periodic assembly and breakdown of the nuclear envelope. As such,…
Lab on a chip (LOC) device intakes fluid and makes it flow through the microchannels, to achieve rapid, highly sensitive and low-cost analysis with significant yield. Graphene has vast potential to be used in LOC devices owing to its…
Protein assembly plays an important role throughout all phyla of life, both physiologically and pathologically. In particular, aggregation and polymerization of proteins are key-strategies that regulate cellular function. In recent years,…
How migratory birds can find the right way in navigating over thousand miles is an intriguing question, which much interested researchers in both fields of biology and physics for centuries. There several putative proposals that sound…
We suggest a 3D phase field model to describe 3D cell spreading on a flat substrate. The model is a simplified version of a minimal model that was developed in [1]. Our model couples the order parameter $u$ with 3D polarization…
We propose theoretical methods to infer coupling strength and noise intensity simultaneously through an observation of spike timing in two well-synchronized noisy oscillators. A phase oscillator model is applied to derive formulae relating…
We study the protein folding problem on the base of the quantum approach we proposed recently by considering the model of protein chain with nine amino-acid residues. We introduced the concept of distance space and its projections on a…
We study a three-dimensional articulated rigid-body biped model that possesses zero cost of transport walking gaits. Energy losses are avoided due to the complete elimination of the foot-ground collisions by the concerted oscillatory motion…
Microtubules are an essential physical building block of cellular systems. They are organized using specific crosslinkers, motors, and influencers of nucleation and growth. With the addition of anti-parallel crosslinkers, microtubule…
Retinal degenerative diseases lead to the blindness of millions of people around the world. In case of age-related macular degeneration (AMD), the atrophy of retinal pigment epithelium (RPE) precedes neural dystrophy. But as crucial as…
The dynamics and spectroscopy of N-methyl-acetamide (NMA) and trialanine in solution is characterized from molecular dynamics (MD) simulations using different energy functions, including a conventional point charge (PC)-based force field,…
In human and animal groups, social interactions often rely on the transmission of information via visual observation of the behavior of others. These visual interactions are governed by the laws of physics and sensory limits. Individuals…
Maze generating and solving are challenging problems in mathematics and computing. Here we generated simple 2X2 maze problems applying four chemicals and created a set of engineered bacteria, which in a mixed population worked as a…
Brain network is remarkably cost-efficient while the fundamental physical and dynamical mechanisms underlying its economical optimization in network structure and activity are not clear. Here we study intricate cost-efficient interplay…