Depth from Defocus (DfD) is the task of estimating a dense metric depth map from a focus stack. Unlike previous works overfitting to a certain dataset, this paper focuses on the challenging and practical setting of zero-shot generalization. We first propose a new real-world DfD benchmark ZEDD, which contains 8.3x more scenes and significantly higher quality images and ground-truth depth maps compared to previous benchmarks. We also design a novel network architecture named FOSSA. FOSSA is a Transformer-based architecture with novel designs tailored to the DfD task. The key contribution is a stack attention layer with a focus distance embedding, allowing efficient information exchange across the focus stack. Finally, we develop a new training data pipeline allowing us to utilize existing large-scale RGBD datasets to generate synthetic focus stacks. Experiment results on ZEDD and other benchmarks show a significant improvement over the baselines, reducing errors by up to 55.7%. The ZEDD benchmark is released at https://zedd.cs.princeton.edu. The code and checkpoints are released at https://github.com/princeton-vl/FOSSA.
@article{arxiv.2603.26658,
title = {Zero-Shot Depth from Defocus},
author = {Yiming Zuo and Hongyu Wen and Venkat Subramanian and Patrick Chen and Karhan Kayan and Mario Bijelic and Felix Heide and Jia Deng},
journal= {arXiv preprint arXiv:2603.26658},
year = {2026}
}