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Using VAEs to Learn Latent Variables: Observations on Applications in cryo-EM

Machine Learning 2023-05-12 v2 Machine Learning Quantitative Methods

Abstract

Variational autoencoders (VAEs) are a popular generative model used to approximate distributions. The encoder part of the VAE is used in amortized learning of latent variables, producing a latent representation for data samples. Recently, VAEs have been used to characterize physical and biological systems. In this case study, we qualitatively examine the amortization properties of a VAE used in biological applications. We find that in this application the encoder bears a qualitative resemblance to more traditional explicit representation of latent variables.

Keywords

Cite

@article{arxiv.2303.07487,
  title  = {Using VAEs to Learn Latent Variables: Observations on Applications in cryo-EM},
  author = {Daniel G. Edelberg and Roy R. Lederman},
  journal= {arXiv preprint arXiv:2303.07487},
  year   = {2023}
}
R2 v1 2026-06-28T09:15:10.762Z