Unzipping DNA : A hypothesis on correlation during replication
Statistical Mechanics
2007-05-23 v2 Soft Condensed Matter
Biological Physics
q-bio
Abstract
Based on the result of an unzipping phase transition by a force in a model of DNA, we hypothesize that the DnaA-type proteins act as a pulling agent with a force slightly less than the critical force for unzipping. The dynamic (space-time) correlation of unzipping then drives the subsequent events of replication. In such a correlation driven scenario, there is no need of a replisome as a structural unit and this elusive replisome may not exist at all.
Keywords
Cite
@article{arxiv.cond-mat/0010132,
title = {Unzipping DNA : A hypothesis on correlation during replication},
author = {Somendra M. Bhattacharjee},
journal= {arXiv preprint arXiv:cond-mat/0010132},
year = {2007}
}
Comments
5 pages, latex/revtex, 1 eps figures. Corrected typos, reference list updated. Proceedings of CMDAYS2K, held at Guru Ghasidas University, Bilaspur, India, Aug 29-31, 2K