Transfer-RNA genes in archaea often have introns intervening between exon sequences. The structural motif at the boundary between exon and intron is the bulge-helix-bulge. Computational investigations of these boundary structures in H. marismortui lead us to propose that tRNA-isoleucine and tRNA-tryptophan genes are co-located. Precise insilico identification of the splice-sites on the bulges at the exon-intron boundaries conduce us to infer that a single intron-containing composite tRNA-gene can give rise to more than one gene produc.
@article{arxiv.q-bio/0510053,
title = {tRNA-isoleucine-tryptophan Composite Gene},
author = {Zhumur Ghosh and Jayprokas Chakrabarti and Bibekanand Mallick and Smarajit Das and Satyabrata Sahoo and Harmeet Singh Sethi},
journal= {arXiv preprint arXiv:q-bio/0510053},
year = {2007}
}