English

Transport threshold in a quantum model for the KscA ion channel

Quantum Physics 2021-12-15 v1

Abstract

The mechanism behind the high throughput rate in K+^{+} channels is still an open problem. Recent simulations have shown that the passage of potassium through the K+^{+} channel core, the so-called selectivity filter (SF), is water-free against models where the strength of Coulomb repulsion freezes ions conduction. It has been suggested that quantum coherent hopping might be relevant in mediating ion conduction. Within the quantum approach and the hypothesis of desolvated ions along the pathway, we start with a number of particles in a source to see how they go across the SF modeled by a linear chain of sites to be collected in a drain. As a main result we show that there is a threshold SF occupancy is three ions on average, which is in agreement with recent classical model simulations.

Keywords

Cite

@article{arxiv.2107.04573,
  title  = {Transport threshold in a quantum model for the KscA ion channel},
  author = {N. De March and S. D. Prado and L. G. Brunnet},
  journal= {arXiv preprint arXiv:2107.04573},
  year   = {2021}
}

Comments

11 pages, 4 figures

R2 v1 2026-06-24T04:03:02.620Z