$\theta$-curves in proteins
Soft Condensed Matter
2019-08-19 v1 Biological Physics
Biomolecules
Abstract
Apart from the knots formed by the main-chain, the proteins can form numerous topological structures, when included the covalent and ion-mediated interactions. In this work, we define the protein non-trivial -curves and identify 7 different topologies in all structures known up to date. We study the correlation of the motif with the function and organism of origin, and pointing the similarity with main-chain knots, we show that some motifs may indeed be functional. We also analyze the folding and bridge-induced stability of an exemplary protein with -curve motif and provide a catalogue of possible -curves in proteins.
Keywords
Cite
@article{arxiv.1908.05919,
title = {$\theta$-curves in proteins},
author = {Pawel Dabrowski-Tumanski and Dimos Goundaroulis and Andrzej Stasiak and Joanna I. Sulkowska},
journal= {arXiv preprint arXiv:1908.05919},
year = {2019}
}