In this work, we investigate the spectra of the prospective tetracharm and tetrabottom baryonium, viz. the baryon-antibaryon states, in the framework of QCD sum rules. The non-perturbative contributions up to dimension 10 are taken into account. Numerical results indicate that there might exist 4 possible tetracharm baryonium states with masses (7.33±0.12), (7.42±0.13), (7.68±0.17), and (7.76±0.12) GeV for the quantum numbers of 0−+, 1−−, 0++, and 1++, respectively. The corresponding tetrabottom partners are found lying respectively at (19.41±0.15), (19.48±0.15), (19.77±0.19) and (19.84±0.19) GeV. Additionally, we also analyze the spectra of the ΞˉbcΞbc and ΞˉccΞbb baryonium states, which lie in the range of 13.77−14.40 GeV and 13.39−14.14 GeV, respectively. The possible baryonium decay modes are analyzed, which are hopefully measurable in LHC experiments.