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The maximum quartet distance between phylogenetic trees

Combinatorics 2026-08-04 v1

Abstract

The quartet distance counts the four-leaf subsets on which two binary phylogenetic trees display different topologies. We prove that its maximum over trees on nn leaves is (2/3+o(1))(n4)(2/3+o(1))\binom{n}{4}, resolving a conjecture of Bandelt and Dress from 1986 and calibrating the scale of a fundamental metric for comparing phylogenetic trees. The proof reduces arbitrary pairs of trees to caterpillars by means of a common-root planarization and an identity on five-leaf trees.

Cite

@article{arxiv.2608.03542,
  title  = {The maximum quartet distance between phylogenetic trees},
  author = {Lior Pachter},
  journal= {arXiv preprint arXiv:2608.03542},
  year   = {2026}
}

Comments

11 pages, 2 figures