The entrance dynamics of polymers into a gel
Statistical Mechanics
2007-05-23 v1 Disordered Systems and Neural Networks
Abstract
We use computer simulations to study the (driven) dynamics of a charged polymer in a disordered medium, thus mimicking the setting used in gel electrophoresis. In agreement with experiments, we find that inside the gel the mobility of the polymer is only a weak function of its length N. In contrast to this, the mean entrance time into the gel, is a very strong function of N, <tau_e > \propto N^1.3, and does not show any sign of saturation with increasing N. We rationalize this effect by means of a simple model and propose an experimental setup that should allow to increase the separation ability of gel electrophoresis significantly.
Cite
@article{arxiv.cond-mat/0006049,
title = {The entrance dynamics of polymers into a gel},
author = {Walter Kob and Leticia F. Cugliandolo},
journal= {arXiv preprint arXiv:cond-mat/0006049},
year = {2007}
}
Comments
7 pages of Latex, 4 figures