English

The energy costs of biological insulators

Molecular Networks 2014-05-06 v2 Cell Behavior

Abstract

Biochemical signaling pathways can be insulated from impedance and competition effects through enzymatic "futile cycles" which consume energy, typically in the form of ATP. We hypothesize that better insulation necessarily requires higher energy consumption, and provide evidence, through the computational analysis of a simplified physical model, to support this hypothesis.

Keywords

Cite

@article{arxiv.1210.3809,
  title  = {The energy costs of biological insulators},
  author = {John Barton and Eduardo D. Sontag},
  journal= {arXiv preprint arXiv:1210.3809},
  year   = {2014}
}

Comments

16 pages, 5 figures