Synthesis of Polyglobalide by Enzymatic Ring Opening Polymerization Using Pressurized Fluids
Abstract
Here, the synthesis of polyglobalide (PGl) by enzymatic ring-opening polymerization (e-ROP) is investigated, using pressurized carbon dioxide (CO2), pressurized CO2 + dichloromethane (DCM), and pressurized propane as solvents. Particularly, the effects of phase equilibrium on the course of e-ROP and PGl final properties are discussed. The partition coefficients of CO2, DCM, propane, globalide and PGl were calculated with help of thermodynamic models, providing proper understanding of monomer partitioning in the reaction system. Reactions performed in pure CO2 resulted in monomer conversions of 100%. Besides, when only one liquid phase was present inside the reactor, PGl samples presented low polydispersities and high average molecular weights. When carried out in CO2 + DCM, e-ROP resulted in lower monomer conversions and PGl samples with higher polydispersities and lower average molecular weights. Finally, reactions carried out in pressurized propane (200 bar) produced PGl samples with the highest average molecular weights among the analyzed products.
Cite
@article{arxiv.2401.05873,
title = {Synthesis of Polyglobalide by Enzymatic Ring Opening Polymerization Using Pressurized Fluids},
author = {Camila Guindani and Wilfred A. G. Jaramillo and Graziâni Candiotto and Evertan A. Rebelatto and Frederico W. Tavares and José Carlos Pinto and Papa M. Ndiaye and Márcio Nele},
journal= {arXiv preprint arXiv:2401.05873},
year = {2024}
}
Comments
41 pages, 9 figures, 8 tables