Synaptic metaplasticity underlies tetanic potentiation in Lymnaea: a novel paradigm
Biological Physics
2014-03-05 v1 Disordered Systems and Neural Networks
Neurons and Cognition
Abstract
We present a mathematical model which explains and interprets a novel form of short-term potentiation, which was found to be use-, but not time-dependent, in experiments done on Lymnaea neurons. The high degree of potentiation is explained using a model of synaptic metaplasticity, while the use-dependence (which is critically reliant on the presence of kinase in the experiment) is explained using a model of a stochastic and bistable biological switch.
Keywords
Cite
@article{arxiv.1310.0218,
title = {Synaptic metaplasticity underlies tetanic potentiation in Lymnaea: a novel paradigm},
author = {Anita Mehta and Jean-Marc Luck and Collin C. Luk and Naweed I. Syed},
journal= {arXiv preprint arXiv:1310.0218},
year = {2014}
}
Comments
12 pages, 7 figures, to appear in PLoS One (2013)