English

SurvHTE-Bench: A Benchmark for Heterogeneous Treatment Effect Estimation in Survival Analysis

Machine Learning 2026-03-06 v1 Artificial Intelligence Machine Learning

Abstract

Estimating heterogeneous treatment effects (HTEs) from right-censored survival data is critical in high-stakes applications such as precision medicine and individualized policy-making. Yet, the survival analysis setting poses unique challenges for HTE estimation due to censoring, unobserved counterfactuals, and complex identification assumptions. Despite recent advances, from Causal Survival Forests to survival meta-learners and outcome imputation approaches, evaluation practices remain fragmented and inconsistent. We introduce SurvHTE-Bench, the first comprehensive benchmark for HTE estimation with censored outcomes. The benchmark spans (i) a modular suite of synthetic datasets with known ground truth, systematically varying causal assumptions and survival dynamics, (ii) semi-synthetic datasets that pair real-world covariates with simulated treatments and outcomes, and (iii) real-world datasets from a twin study (with known ground truth) and from an HIV clinical trial. Across synthetic, semi-synthetic, and real-world settings, we provide the first rigorous comparison of survival HTE methods under diverse conditions and realistic assumption violations. SurvHTE-Bench establishes a foundation for fair, reproducible, and extensible evaluation of causal survival methods. The data and code of our benchmark are available at: https://github.com/Shahriarnz14/SurvHTE-Bench .

Keywords

Cite

@article{arxiv.2603.05483,
  title  = {SurvHTE-Bench: A Benchmark for Heterogeneous Treatment Effect Estimation in Survival Analysis},
  author = {Shahriar Noroozizadeh and Xiaobin Shen and Jeremy C. Weiss and George H. Chen},
  journal= {arXiv preprint arXiv:2603.05483},
  year   = {2026}
}

Comments

The Fourteenth International Conference on Learning Representations (ICLR 2026)