Sub-nanometer measurement of transient structural changes in dye-doped polystyrene microspheres
Optics
2022-09-02 v1
Abstract
We present an interferometric spectral-domain optical coherence tomography microscopy setup to detect structural changes using interference of light reflected from different interfaces of the sample. We induce a reproducible nanometer-scale size change in dye-doped 10m polystyrene microspheres by the release of Stokes shift energy of dye molecules inside the microspheres, excited by a modulated 532-nm laser. The resulting optical path length difference was measured with a sensitivity of 0.4 limited by photodetection noise, and reveals elastic as well as inelastic responses, which opens up possibilities for measuring the response of cell-sized biological objects.
Cite
@article{arxiv.2209.00356,
title = {Sub-nanometer measurement of transient structural changes in dye-doped polystyrene microspheres},
author = {Pegah Asgari and Itir Bakiş Dogru Yüksel and Gerhard A. Blab and Hans C. Gerritsen and Allard P. Mosk},
journal= {arXiv preprint arXiv:2209.00356},
year = {2022}
}