Structure theorems for actions of homeomorphism groups

We give general classification and structure theorems for actions of groups of homeomorphisms and diffeomorphisms on manifolds, reminiscent of classical results for actions of (locally) compact groups. This gives a negative answer to Ghys' "extension problem" for diffeomorphisms of manifolds with boundary, as well as a classification of all homomorphisma $\mathrm{Homeo}_0(M) \to \mathrm{Homeo}_0(N)$ when dim(M) = dim(N) (and related results for diffeomorphisms), and a complete classification of actions of $\mathrm{Homeo}_0(S^1)$ on surfaces. This resolves many problems in a program initiated by Ghys, and gives definitive answers to conjectures of Militon and Hurtado and a question of Rubin.