English

SpO$_2$ Predictor-Guided Stage-Wise Time-Frequency Reconstruction of Low-Quality Dual-Wavelength PPG for Oxygen Saturation Estimation

Signal Processing 2026-07-09 v1 Artificial Intelligence Machine Learning

Abstract

Continuous oxygen saturation (SpO2_2) estimation from wearable photoplethysmography (PPG) is important for long-term health monitoring, but low-quality red and infrared PPG segments can distort waveform morphology and degrade SpO2_2 prediction accuracy. Existing PPG denoising and reconstruction methods usually optimize waveform fidelity or heart rate characteristics, while time-domain waveform loss on PPG signals alone insufficiently preserves frequency structure and SpO2_2-relevant information. This paper proposes a SpO2_2 predictor-guided stage-wise time-frequency reconstruction framework for low-quality dual-wavelength PPG signals. The proposed method first selects high-quality PPG segments to pretrain a SpO2_2 predictor. A masked reconstruction model is then trained to recover randomly masked PPG regions using a joint reconstruction objective that combines time-domain waveform loss with frequency-domain loss computed from the short-time Fourier transform (STFT). To make the reconstruction task physiologically relevant, the pretrained SpO2_2 predictor is incorporated as an additional constraint, encouraging the reconstructed PPG to preserve SpO2_2 information rather than only minimizing waveform reconstruction error. The SpO2_2 predictor and PPG reconstructor model are optimized through four training stages. Experiments on the public OpenOximetry Repository and a private wearable PPG dataset show that the proposed approach achieves the lowest subject-level MAE, with 2.882\% on the public dataset and 2.359\% on the private dataset.

Keywords

Cite

@article{arxiv.2607.07996,
  title  = {SpO$_2$ Predictor-Guided Stage-Wise Time-Frequency Reconstruction of Low-Quality Dual-Wavelength PPG for Oxygen Saturation Estimation},
  author = {Zequan Liang and Elahe Hosseini and Ning Miao and Mahdi Pirayesh Shirazi Nejad and Wei Shao and Ehsan Kourkchi and Setareh Rafatirad and Houman Homayoun},
  journal= {arXiv preprint arXiv:2607.07996},
  year   = {2026}
}