Spectral Analysis of Protein-Protein Interactions in Drosophila melanogaster
Molecular Networks
2009-11-10 v1 Statistical Mechanics
Abstract
Within a case study on the protein-protein interaction network (PIN) of Drosophila melanogaster we investigate the relation between the network's spectral properties and its structural features such as the prevalence of specific subgraphs or duplicate nodes as a result of its evolutionary history. The discrete part of the spectral density shows fingerprints of the PIN's topological features including a preference for loop structures. Duplicate nodes are another prominent feature of PINs and we discuss their representation in the PIN's spectrum as well as their biological implications.
Keywords
Cite
@article{arxiv.q-bio/0405021,
title = {Spectral Analysis of Protein-Protein Interactions in Drosophila melanogaster},
author = {Christel Kamp and Kim Christensen},
journal= {arXiv preprint arXiv:q-bio/0405021},
year = {2009}
}
Comments
9 pages RevTeX including 8 figures