English

Solvable senescence model with positive mutations

Populations and Evolution 2007-05-23 v1

Abstract

We build upon our previous analytical results for the Penna model of senescence to include positive mutations. We investigate whether a small but non-zero positive mutation rate gives qualitatively different results to the traditional Penna model in which no positive mutations are considered. We find that the high-lifespan tail of the distribution is radically changed in structure, but that there is not much effect on the bulk of the population. Th e mortality plateau that we found previously for a stochastic generalization of the Penna model is stable to a small positive mutation rate.

Keywords

Cite

@article{arxiv.q-bio/0411002,
  title  = {Solvable senescence model with positive mutations},
  author = {J. B. Coe and Y. Mao and M. E. Cates},
  journal= {arXiv preprint arXiv:q-bio/0411002},
  year   = {2007}
}

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