English

Single-Base DNA Discrimination via Transverse Ionic Transport

Biological Physics 2015-06-16 v2 Soft Condensed Matter Biomolecules

Abstract

We suggest to discriminate single DNA bases via transverse ionic transport, namely by detecting the ionic current that flows in a channel while a single-stranded DNA is driven through an intersecting nanochannel. Our all-atom molecular dynamics simulations indeed show that the ionic currents of the four bases are statistically distinct, thus offering another possible approach to sequence DNA.

Keywords

Cite

@article{arxiv.1307.0055,
  title  = {Single-Base DNA Discrimination via Transverse Ionic Transport},
  author = {James Wilson and M. Di Ventra},
  journal= {arXiv preprint arXiv:1307.0055},
  year   = {2015}
}

Comments

5 pages, 3 figures

R2 v1 2026-06-22T00:42:45.262Z