English

SIAN: software for structural identifiability analysis of ODE models

Symbolic Computation 2020-11-17 v1 Systems and Control Dynamical Systems Quantitative Methods

Abstract

Biological processes are often modeled by ordinary differential equations with unknown parameters. The unknown parameters are usually estimated from experimental data. In some cases, due to the structure of the model, this estimation problem does not have a unique solution even in the case of continuous noise-free data. It is therefore desirable to check the uniqueness a priori before carrying out actual experiments. We present a new software SIAN (Structural Identifiability ANalyser) that does this. Our software can tackle problems that could not be tackled by previously developed packages.

Cite

@article{arxiv.1812.10180,
  title  = {SIAN: software for structural identifiability analysis of ODE models},
  author = {Hoon Hong and Alexey Ovchinnikov and Gleb Pogudin and Chee Yap},
  journal= {arXiv preprint arXiv:1812.10180},
  year   = {2020}
}

Comments

This article has been accepted for publication in Bioinformatics published by Oxford University Press

R2 v1 2026-06-23T06:55:58.772Z