Short-Range Migration Can Alter Evolutionary Dynamics in Solid Tumors
Populations and Evolution
2019-12-05 v1 Soft Condensed Matter
Biological Physics
Tissues and Organs
Abstract
Here, we investigate how competition in the Eden model is affected by short range dispersal and the requirement that site updates occur only after several updates of the same site have been attempted previously. The latter models the effect of tissue or media resistance to invasion. We found that the existence of tissue intensifies 'Natural Selection' and de-accelerating 'Genetic Drift', both to a limited extent. More interestingly, our results show that short-range migration can eliminate Genetic demixing and conceal Natural Selection.
Keywords
Cite
@article{arxiv.1909.11597,
title = {Short-Range Migration Can Alter Evolutionary Dynamics in Solid Tumors},
author = {Youness Azimzade and Abbas Ali Saberi},
journal= {arXiv preprint arXiv:1909.11597},
year = {2019}
}
Comments
8 pages, 6 figures (to appear in JSTAT)